Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 19/20 | 0.67 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20022236 | 1.00 | STING1 (0.67) | STING1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL1590345 | 0.89 | STING1 (0.61) | STING1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL29636424 | 0.88 | STING1 (0.71) | STING1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL20022235 | 0.88 | STING1 (0.71) | STING1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL20022234 | 0.86 | STING1 (0.65) | STING1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL29636383 | 0.86 | STING1 (0.65) | STING1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL20022264 | 0.83 | STING1 (0.64) | STING1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL21452735 | 0.83 | STING1 (0.49) | STING1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL29636390 | 0.83 | STING1 (0.64) | STING1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL20026418 | 0.82 | STING1 (0.61) | STING1HDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110036001-B | Benzo [ b ] thiophene compounds as STING agonists | 默沙东公司 | 2022-03-22 | — | — | CN | disclosed |