Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 2/20 | 0.51 |
| ▸ | ACP1 | P24666 | 9/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | RAD52 | P43351 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.46 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23015131 | 1.00 | SLC2A1 (0.51) | SLC2A1ACP1KDM4EALDH1A1POLB | |
| SCHEMBL29636840 | 0.92 | ACP1 (0.44) | SLC2A1ACP1KDM4EALDH1A1LMNA | |
| SCHEMBL23015198 | 0.92 | ACP1 (0.44) | SLC2A1ACP1KDM4EALDH1A1LMNA | |
| SCHEMBL29636793 | 0.90 | ACP1 (0.47) | SLC2A1ACP1KDM1AEHMT2RCOR1 | |
| SCHEMBL23015171 | 0.90 | ACP1 (0.47) | SLC2A1ACP1KDM1AEHMT2RCOR1 | |
| SCHEMBL23015284 | 0.88 | EHMT2 (0.59) | SLC2A1KDM1AEHMT2RCOR1 | |
| SCHEMBL29636825 | 0.87 | ACP1 (0.44) | SLC2A1ACP1KDM4EALDH1A1POLB | |
| SCHEMBL23015290 | 0.85 | SLC2A1 (0.52) | SLC2A1ACP1KDM4EALDH1A1POLB | |
| SCHEMBL6751610 | 0.84 | SLC2A1 (0.61) | SLC2A1ACP1KDM4EALDH1A1POLB | |
| SCHEMBL23015096 | 0.83 | ACP1 (0.50) | SLC2A1ACP1KDM4EALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4017492-A1 | MOLECULES THAT BIND TO TDP-43 FOR THE TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS AND RELATED DISORDERS | Biohaven Therapeutics Ltd. (US) | 2022-06-29 | — | — | EP | disclosed |