Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | GLA | P06280 | 4/20 | 0.61 |
| ▸ | GAA | P10253 | 4/20 | 0.61 |
| ▸ | HPGD | P15428 | 3/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 6/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | RAB9A | P51151 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | LCK | P06239 | 2/20 | 0.45 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | EPHB3 | P54753 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21616815 | 1.00 | KDM4E (0.61) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL21622873 | 0.89 | NPC1 (0.58) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL21622870 | 0.80 | LCK (0.52) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL21622752 | 0.77 | NPC1 (0.44) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL21622753 | 0.75 | NPC1 (0.47) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL21622729 | 0.75 | LCK (0.53) | ALDH1A1GAAHPGDHSD17B10NPC1 | |
| SCHEMBL21622730 | 0.75 | NPC1 (0.50) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL21623398 | 0.74 | MAPK8 (0.44) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL23917391 | 0.72 | KDM4E (0.59) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL18934624 | 0.71 | MAPK8 (0.41) | KDM4EALDH1A1HPGDNPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112384595-B | Material for organic electroluminescent device | 默克专利有限公司 | 2024-05-28 | — | — | CN | disclosed |
| EP-4046208-A1 | ELECTRONIC DEVICES | Merck Patent GmbH (DE) | 2022-08-24 | — | — | EP | disclosed |
| EP-3820966-B1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2022-06-08 | — | — | EP | disclosed |
| CN-114586190-A | Electronic device | 默克专利有限公司 | 2022-06-03 | — | — | CN | disclosed |