Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A3 | O15427 | 6/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21551673 | 1.00 | SLC16A3 (0.58) | SLC16A3KCNH2KDM4ETSHRHSD17B10 | |
| SCHEMBL21551671 | 1.00 | SLC16A3 (0.58) | SLC16A3KCNH2KDM4ETSHRHSD17B10 | |
| SCHEMBL21550478 | 0.88 | SLC16A3 (0.62) | SLC16A3KCNH2KDM4ETSHRHSD17B10 | |
| SCHEMBL29637406 | 0.88 | SLC16A3 (0.62) | SLC16A3KCNH2KDM4ETSHRHSD17B10 | |
| SCHEMBL21550479 | 0.88 | SLC16A3 (0.62) | SLC16A3KCNH2KDM4ETSHRHSD17B10 | |
| SCHEMBL21551528 | 0.85 | SLC16A3 (0.59) | SLC16A3KCNH2KDM4ETSHRHSD17B10 | |
| SCHEMBL21551527 | 0.85 | SLC16A3 (0.59) | SLC16A3KCNH2KDM4ETSHRHSD17B10 | |
| SCHEMBL21557901 | 0.84 | SLC16A3 (0.59) | SLC16A3KCNH2KDM4ETSHRHSD17B10 | |
| SCHEMBL21557902 | 0.84 | SLC16A3 (0.59) | SLC16A3KCNH2KDM4ETSHRHSD17B10 | |
| SCHEMBL23116358 | 0.83 | SLC16A3 (0.55) | SLC16A3KCNH2KDM4ETSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115028637-B | Triazolopyrimidine compounds and their use for the treatment of cancer | 迪哲(江苏)医药股份有限公司 | 2024-03-22 | — | — | CN | disclosed |
| CN-115028637-A | Triazolopyrimidine compounds and their use for the treatment of cancer | 迪哲(江苏)医药股份有限公司 | 2022-09-09 | — | — | CN | disclosed |
| CN-115028636-A | Triazolopyrimidine compounds and their use for the treatment of cancer | 迪哲(江苏)医药股份有限公司 | 2022-09-09 | — | — | CN | disclosed |
| EP-3790879-B1 | TRIAZOLOPYRIMIDINE COMPOUNDS AND THEIR USE IN TREATING CANCER | DIZAL JIANGSU PHARMACEUTICAL CO LTD (CN) | 2022-06-29 | — | — | EP | disclosed |
| CN-112469721-B | Triazolopyrimidine compounds and their use for the treatment of cancer | 迪哲(江苏)医药股份有限公司 | 2022-06-07 | — | — | CN | disclosed |