Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 2/20 | 0.45 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.42 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.42 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3827645 | 1.00 | ADORA1 (0.45) | ADORA1PRKAG1PRKAA1PRKAB1POLB | |
| SCHEMBL3827648 | 1.00 | ADORA1 (0.45) | ADORA1PRKAG1PRKAA1PRKAB1POLB | |
| SCHEMBL3822659 | 0.93 | TYMP (0.47) | ADORA1 | |
| SCHEMBL3821904 | 0.90 | TYMP (0.39) | ADORA1 | |
| SCHEMBL3821907 | 0.90 | TYMP (0.39) | ADORA1 | |
| SCHEMBL24513540 | 0.88 | P2RY12 (0.42) | — | |
| SCHEMBL29637929 | 0.88 | P2RY12 (0.42) | — | |
| SCHEMBL31629565 | 0.87 | POLB (0.49) | ADORA1POLB | |
| SCHEMBL21577261 | 0.86 | TYMP (0.46) | POLB | |
| SCHEMBL3824084 | 0.85 | TYMP (0.58) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4259798-A1 | POLY-MORPHOLINO OLIGONUCLEOTIDE GAPMERS | Eisai R&D Management Co., Ltd. (JP) | 2023-10-18 | — | — | EP | disclosed |
| WO-2022125984-A1 | TAU-TARGETING OLIGONUCLEOTIDE GAPMERS | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2022-06-16 | — | — | WO | disclosed |
| WO-2022125987-A1 | POLY-MORPHOLINO OLIGONUCLEOTIDE GAPMERS | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2022-06-16 | — | — | WO | disclosed |