SCHEMBL29638062

CC(C)C[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CO)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@H](CC(=O)O)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CC(=O)O)C(C)C)[C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)O

nearest known ligand 0.78

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	GLP1R	P43220	9/20	0.74

▸	GCGR	P47871	3/20	0.74

▸	NPY1R	P25929	1/20	0.72

▸	NPY2R	P49146	1/20	0.72

▸	NPY4R	P50391	1/20	0.72

▸	NPY5R	Q15761	1/20	0.72

▸	C5AR1	P21730	1/20	0.70

▸	CXCR4	P61073	5/20	0.67

▸	CCKBR	P32239	2/20	0.67

▸	CALCR	P30988	2/20	0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29638067	1.00	GLP1R (0.74)	GLP1RGCGRNPY1RNPY2RNPY4R
SCHEMBL30932068	0.95	NPY1R (0.72)	GLP1RGCGRNPY1RNPY2RNPY4R
SCHEMBL30432159	0.94	C5AR1 (0.73)	GLP1RGCGRNPY1RNPY2RNPY4R
SCHEMBL29429583	0.94	NPY1R (0.74)	GLP1RGCGRNPY1RNPY2RNPY4R
SCHEMBL29429581	0.94	NPY1R (0.74)	GLP1RGCGRNPY1RNPY2RNPY4R
SCHEMBL30403572	0.94	GLP1R (0.73)	GLP1RGCGRNPY1RNPY2RNPY4R
SCHEMBL31182680	0.93	GLP1R (0.74)	GLP1RGCGRNPY1RNPY2RNPY4R
SCHEMBL30429341	0.93	GLP1R (0.68)	GLP1RGCGRNPY1RNPY2RNPY4R
SCHEMBL31000945	0.93	C5AR1 (0.73)	GLP1RGCGRNPY1RNPY2RNPY4R
SCHEMBL30801072	0.93	GLP1R (0.71)	GLP1RGCGRNPY1RNPY2RNPY4R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-4591934-A2	VARIANTS OF C-TYPE NATRIURETIC PEPTIDE	BioMarin Pharmaceutical Inc. (US)	2025-07-30	—	—	EP	disclosed
EP-4019038-A2	USE OF C-TYPE NATRIURETIC PEPTIDE VARIANTS TO TREAT OSTEOARTHRITIS	BioMarin Pharmaceutical Inc. (US)	2022-06-29	—	—	EP	disclosed