Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22954806 | 1.00 | NPC1 (0.46) | NPC1RAB9AMAPTSMN1; SMN2MEN1 | |
| SCHEMBL22955378 | 0.92 | MAPT (0.42) | NPC1RAB9AMAPTSMN1; SMN2MEN1 | |
| SCHEMBL23665983 | 0.87 | MAPT (0.45) | MAPTLMNAPKM | |
| SCHEMBL29638148 | 0.86 | NPC1 (0.43) | NPC1RAB9AMAPTSMN1; SMN2LMNA | |
| SCHEMBL22955321 | 0.86 | NPC1 (0.43) | NPC1RAB9AMAPTSMN1; SMN2LMNA | |
| SCHEMBL22954807 | 0.85 | NPC1 (0.37) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL29638152 | 0.85 | NPC1 (0.37) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL23666476 | 0.85 | USP7 (0.33) | NPC1RAB9A | |
| SCHEMBL22954869 | 0.84 | NPC1 (0.40) | NPC1RAB9AMAPTLMNA | |
| SCHEMBL22954803 | 0.83 | CYP1A2 (0.41) | LMNAL3MBTL1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110317177-B | Preparation method of pyrimidine salicylic acid oxime ester compound and application of pyrimidine salicylic acid oxime ester compound as herbicide | 常州大学 | 2022-05-17 | — | — | CN | claimed |
| CN-110317177-B | Preparation method of pyrimidine salicylic acid oxime ester compound and application of pyrimidine salicylic acid oxime ester compound as herbicide | 常州大学 | 2022-05-17 | — | — | CN | disclosed |