Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | PLK4 | O00444 | 2/20 | 0.56 |
| ▸ | KDR | P35968 | 2/20 | 0.53 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.51 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.51 |
| ▸ | CDK1 | P06493 | 1/20 | 0.51 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.51 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.51 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.51 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.51 |
| ▸ | PLK1 | P53350 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14674714 | 0.89 | FLT3 (0.61) | FLT3MEN1KMT2APLK4KDR | |
| SCHEMBL14674715 | 0.89 | FLT3 (0.61) | FLT3MEN1KMT2APLK4KDR | |
| SCHEMBL29638300 | 0.89 | FLT3 (0.61) | FLT3MEN1KMT2APLK4KDR | |
| SCHEMBL3748098 | 0.88 | FLT3 (0.56) | FLT3MEN1KMT2APLK4KDR | |
| SCHEMBL13929132 | 0.85 | LRRK2 (0.67) | FLT3MEN1KMT2AKDRLRRK2 | |
| SCHEMBL4722687 | 0.85 | LRRK2 (0.67) | FLT3MEN1KMT2AKDRLRRK2 | |
| SCHEMBL29638270 | 0.85 | LRRK2 (0.67) | FLT3MEN1KMT2AKDRLRRK2 | |
| SCHEMBL29638266 | 0.85 | MEN1 (0.62) | FLT3MEN1KMT2APLK4KDR | |
| SCHEMBL3755030 | 0.85 | FLT3 (0.71) | FLT3MEN1KMT2AKDRLRRK2 | |
| SCHEMBL3755027 | 0.85 | FLT3 (0.71) | FLT3MEN1KMT2AKDRLRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111116452-B | Indolone derivatives with alpha-glucosidase inhibitory activity as well as preparation method and application thereof | 五邑大学 | 2022-05-03 | — | — | CN | disclosed |