Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA3 | P51812 | 5/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.72 |
| ▸ | MAPT | P10636 | 1/20 | 0.72 |
| ▸ | GSK3B | P49841 | 2/20 | 0.66 |
| ▸ | FLT3 | P36888 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | CDK2 | P24941 | 3/20 | 0.53 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.53 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.52 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.52 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.52 |
| ▸ | PAK4 | O96013 | 1/20 | 0.52 |
| ▸ | KDR | P35968 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5728155 | 0.89 | RPS6KA3 (0.68) | RPS6KA3ALDH1A1MAPTGSK3BMEN1 | |
| SCHEMBL5728158 | 0.89 | RPS6KA3 (0.68) | RPS6KA3ALDH1A1MAPTGSK3BMEN1 | |
| SCHEMBL5359074 | 0.84 | MAPT (0.72) | RPS6KA3ALDH1A1MAPTGSK3BMEN1 | |
| SCHEMBL17179633 | 0.84 | MAPT (1.00) | RPS6KA3ALDH1A1MAPTGSK3BMEN1 | |
| SCHEMBL6835408 | 0.84 | RPS6KA3 (1.00) | RPS6KA3ALDH1A1MAPTGSK3BMEN1 | |
| SCHEMBL18499299 | 0.84 | RPS6KA3 (1.00) | RPS6KA3ALDH1A1MAPTGSK3BFLT3 | |
| SCHEMBL6849771 | 0.84 | RPS6KA3 (1.00) | RPS6KA3ALDH1A1MAPTGSK3BMEN1 | |
| SCHEMBL13080516 | 0.84 | RPS6KA3 (1.00) | RPS6KA3ALDH1A1MAPTGSK3BMEN1 | |
| SCHEMBL20839 | 0.81 | RPS6KA3 (1.00) | RPS6KA3ALDH1A1MAPTGSK3BFLT3 | |
| SCHEMBL905690 | 0.81 | RPS6KA3 (1.00) | RPS6KA3ALDH1A1MAPTGSK3BFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111116452-B | Indolone derivatives with alpha-glucosidase inhibitory activity as well as preparation method and application thereof | 五邑大学 | 2022-05-03 | — | — | CN | disclosed |