Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | PLK1 | P53350 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.38 |
| ▸ | PRKDC | P78527 | 3/20 | 0.38 |
| ▸ | EGFR | P00533 | 6/20 | 0.38 |
| ▸ | ERBB3 | P21860 | 5/20 | 0.38 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.37 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24557278 | 1.00 | MEN1 (0.39) | MEN1RAB9AKMT2ANPC1PLK1 | |
| SCHEMBL24557285 | 0.90 | PLK1 (0.41) | MEN1RAB9AKMT2ANPC1PLK1 | |
| SCHEMBL29638426 | 0.90 | PLK1 (0.41) | MEN1RAB9AKMT2ANPC1PLK1 | |
| SCHEMBL29638395 | 0.87 | LYN (0.42) | MEN1RAB9AKMT2ANPC1PLK1 | |
| SCHEMBL24557289 | 0.87 | LYN (0.42) | MEN1RAB9AKMT2ANPC1PLK1 | |
| SCHEMBL24557279 | 0.86 | MEN1 (0.42) | MEN1RAB9AKMT2APLK1PIK3CA | |
| SCHEMBL29638478 | 0.86 | MEN1 (0.42) | MEN1RAB9AKMT2APLK1PIK3CA | |
| SCHEMBL24557271 | 0.86 | SRC (0.46) | MEN1RAB9AKMT2APLK1PIK3CA | |
| SCHEMBL29638496 | 0.86 | SRC (0.46) | MEN1RAB9AKMT2APLK1PIK3CA | |
| SCHEMBL24557282 | 0.84 | POLB (0.42) | MEN1RAB9AKMT2APLK1PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022136914-A1 | TYK2 INHIBITORS AND USES THEREOF | SUDO BIOSCIENCES LIMITED (GB) | 2022-06-30 | — | — | WO | disclosed |