Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 14/20 | 0.48 |
| ▸ | SRC | P12931 | 8/20 | 0.48 |
| ▸ | LYN | P07948 | 5/20 | 0.48 |
| ▸ | JAK2 | O60674 | 4/20 | 0.39 |
| ▸ | JAK1 | P23458 | 4/20 | 0.39 |
| ▸ | TYK2 | P29597 | 4/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24557322 | 1.00 | BTK (0.48) | BTKSRCLYNJAK2JAK1 | |
| SCHEMBL29638493 | 0.88 | BTK (0.44) | BTKSRCLYNJAK2JAK1 | |
| SCHEMBL29638407 | 0.88 | BTK (0.48) | BTKSRCLYNJAK2JAK1 | |
| SCHEMBL24557321 | 0.88 | BTK (0.48) | BTKSRCLYNJAK2JAK1 | |
| SCHEMBL29638410 | 0.86 | JAK1 (0.46) | BTKSRCLYNJAK2JAK1 | |
| SCHEMBL24557309 | 0.86 | JAK1 (0.46) | BTKSRCLYNJAK2JAK1 | |
| SCHEMBL24557362 | 0.85 | TYK2 (0.48) | BTKSRCLYNJAK2JAK1 | |
| SCHEMBL29638386 | 0.85 | TYK2 (0.48) | BTKSRCLYNJAK2JAK1 | |
| SCHEMBL29638318 | 0.83 | BTK (0.53) | BTKSRCLYNJAK2JAK1 | |
| SCHEMBL24557265 | 0.82 | JAK1 (0.43) | BTKSRCLYNJAK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022136914-A1 | TYK2 INHIBITORS AND USES THEREOF | SUDO BIOSCIENCES LIMITED (GB) | 2022-06-30 | — | — | WO | disclosed |