Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LYN | P07948 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | BTK | Q06187 | 1/20 | 0.40 |
| ▸ | PLK1 | P53350 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.39 |
| ▸ | PRKDC | P78527 | 3/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | DCTPP1 | Q9H773 | 2/20 | 0.37 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24557288 | 1.00 | LYN (0.40) | LYNSRCBTKPLK1EGFR | |
| SCHEMBL24557286 | 0.91 | LYN (0.48) | LYNSRCBTKPLK1EGFR | |
| SCHEMBL29638313 | 0.91 | LYN (0.48) | LYNSRCBTKPLK1EGFR | |
| SCHEMBL29638478 | 0.89 | MEN1 (0.42) | LYNSRCBTKPLK1MEN1 | |
| SCHEMBL24557279 | 0.89 | MEN1 (0.42) | LYNSRCBTKPLK1MEN1 | |
| SCHEMBL24557308 | 0.88 | TYK2 (0.40) | PLK1MEN1MAPTKMT2APIK3CA | |
| SCHEMBL29638404 | 0.88 | TYK2 (0.40) | PLK1MEN1MAPTKMT2APIK3CA | |
| SCHEMBL24557289 | 0.85 | LYN (0.42) | LYNSRCBTKPLK1MEN1 | |
| SCHEMBL29638395 | 0.85 | LYN (0.42) | LYNSRCBTKPLK1MEN1 | |
| SCHEMBL24557282 | 0.85 | POLB (0.42) | LYNSRCBTKPLK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022136914-A1 | TYK2 INHIBITORS AND USES THEREOF | SUDO BIOSCIENCES LIMITED (GB) | 2022-06-30 | — | — | WO | disclosed |