Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 6/20 | 0.41 |
| ▸ | JAK1 | P23458 | 5/20 | 0.41 |
| ▸ | BTK | Q06187 | 11/20 | 0.40 |
| ▸ | SRC | P12931 | 8/20 | 0.40 |
| ▸ | LYN | P07948 | 6/20 | 0.38 |
| ▸ | JAK2 | O60674 | 2/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29638389 | 0.89 | BTK (0.48) | TYK2JAK1BTKSRCLYN | |
| SCHEMBL29638420 | 0.87 | BTK (0.47) | TYK2JAK1BTKSRCLYN | |
| SCHEMBL29638317 | 0.85 | TYK2 (0.42) | TYK2JAK1JAK2PIK3CA | |
| SCHEMBL24557265 | 0.84 | JAK1 (0.43) | TYK2JAK1BTKSRCLYN | |
| SCHEMBL29638331 | 0.84 | JAK1 (0.43) | TYK2JAK1BTKSRCLYN | |
| SCHEMBL24557309 | 0.84 | JAK1 (0.46) | TYK2JAK1BTKSRCLYN | |
| SCHEMBL29638410 | 0.84 | JAK1 (0.46) | TYK2JAK1BTKSRCLYN | |
| SCHEMBL29638493 | 0.80 | BTK (0.44) | TYK2JAK1BTKSRCLYN | |
| SCHEMBL24557321 | 0.79 | BTK (0.48) | TYK2JAK1BTKSRCLYN | |
| SCHEMBL29638407 | 0.79 | BTK (0.48) | TYK2JAK1BTKSRCLYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022136914-A1 | TYK2 INHIBITORS AND USES THEREOF | SUDO BIOSCIENCES LIMITED (GB) | 2022-06-30 | — | — | WO | disclosed |