Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 10/20 | 0.45 |
| ▸ | SRC | P12931 | 7/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.42 |
| ▸ | PRKDC | P78527 | 2/20 | 0.42 |
| ▸ | LYN | P07948 | 5/20 | 0.41 |
| ▸ | JAK1 | P23458 | 2/20 | 0.40 |
| ▸ | TYK2 | P29597 | 2/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PLK1 | P53350 | 1/20 | 0.39 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24557272 | 1.00 | BTK (0.45) | BTKSRCPIK3CAPRKDCLYN | |
| SCHEMBL29638496 | 0.91 | SRC (0.46) | BTKSRCPIK3CAPRKDCLYN | |
| SCHEMBL24557271 | 0.91 | SRC (0.46) | BTKSRCPIK3CAPRKDCLYN | |
| SCHEMBL29638492 | 0.88 | BTK (0.48) | BTKSRCLYN | |
| SCHEMBL29638399 | 0.88 | BTK (0.43) | BTKSRCPIK3CAPRKDCLYN | |
| SCHEMBL24557280 | 0.87 | TNNI3K (0.39) | BTKSRCPIK3CAPRKDCLYN | |
| SCHEMBL29638322 | 0.87 | TNNI3K (0.39) | BTKSRCPIK3CAPRKDCLYN | |
| SCHEMBL24557282 | 0.87 | POLB (0.42) | BTKSRCPIK3CAPRKDCLYN | |
| SCHEMBL29638556 | 0.87 | POLB (0.42) | BTKSRCPIK3CAPRKDCLYN | |
| SCHEMBL24557279 | 0.86 | MEN1 (0.42) | BTKSRCPIK3CAPRKDCLYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022136914-A1 | TYK2 INHIBITORS AND USES THEREOF | SUDO BIOSCIENCES LIMITED (GB) | 2022-06-30 | — | — | WO | disclosed |