SCHEMBL29638616 — predicted protein targets

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	BRAF	P15056	13/20	0.56

▸	CSF1R	P07333	12/20	0.56

▸	RAF1	P04049	11/20	0.56

▸	DDR2	Q16832	6/20	0.56

▸	DDR1	Q08345	5/20	0.56

▸	ARAF	P10398	1/20	0.56

▸	CYP2C9	P11712	1/20	0.39

▸	FGFR1	P11362	1/20	0.39

▸	KDR	P35968	1/20	0.39

▸	TEK	Q02763	1/20	0.39

▸	MELK	Q14680	1/20	0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL24399584	1.00	BRAF (0.56)	BRAFCSF1RRAF1DDR2DDR1
SCHEMBL24399748	0.90	BRAF (0.56)	BRAFCSF1RRAF1DDR2DDR1
SCHEMBL29638546	0.90	BRAF (0.56)	BRAFCSF1RRAF1DDR2DDR1
SCHEMBL29638747	0.90	BRAF (0.60)	BRAFCSF1RRAF1DDR2DDR1
SCHEMBL24399549	0.90	BRAF (0.60)	BRAFCSF1RRAF1DDR2DDR1
SCHEMBL24399664	0.88	BRAF (0.65)	BRAFCSF1RRAF1DDR2DDR1
SCHEMBL29638547	0.88	BRAF (0.65)	BRAFCSF1RRAF1DDR2DDR1
SCHEMBL24399550	0.86	BRAF (0.63)	BRAFCSF1RRAF1DDR2DDR1
SCHEMBL25374865	0.86	BRAF (0.58)	BRAFCSF1RRAF1DDR2DDR1
SCHEMBL29638524	0.86	BRAF (0.58)	BRAFCSF1RRAF1DDR2DDR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2022089219-A1	ARYLAMIDE COMPOUND, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND PREPARATION METHOD THEREFOR AND USE THEREOF	四川科伦博泰生物医药股份有限公司	2022-05-05	—	—	WO	disclosed