Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 9/20 | 0.48 |
| ▸ | BRAF | P15056 | 9/20 | 0.48 |
| ▸ | CSF1R | P07333 | 6/20 | 0.48 |
| ▸ | DDR1 | Q08345 | 5/20 | 0.48 |
| ▸ | DDR2 | Q16832 | 5/20 | 0.48 |
| ▸ | ARAF | P10398 | 1/20 | 0.48 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | NUDT1 | P36639 | 4/20 | 0.36 |
| ▸ | FLT1 | P17948 | 3/20 | 0.35 |
| ▸ | KDR | P35968 | 3/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.35 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.34 |
| ▸ | FLT4 | P35916 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25378805 | 1.00 | RAF1 (0.48) | RAF1BRAFCSF1RDDR1DDR2 | |
| SCHEMBL25373039 | 0.90 | RAF1 (0.49) | RAF1BRAFCSF1RDDR1DDR2 | |
| SCHEMBL29638609 | 0.90 | RAF1 (0.49) | RAF1BRAFCSF1RDDR1DDR2 | |
| SCHEMBL29638551 | 0.89 | RAF1 (0.48) | RAF1BRAFCSF1RDDR1DDR2 | |
| SCHEMBL24399719 | 0.89 | RAF1 (0.48) | RAF1BRAFCSF1RDDR1DDR2 | |
| SCHEMBL24399761 | 0.88 | BRAF (0.56) | RAF1BRAFCSF1RDDR1DDR2 | |
| SCHEMBL29638586 | 0.88 | BRAF (0.56) | RAF1BRAFCSF1RDDR1DDR2 | |
| SCHEMBL24399605 | 0.88 | RAF1 (0.63) | RAF1BRAFCSF1RDDR1DDR2 | |
| SCHEMBL29638514 | 0.88 | RAF1 (0.63) | RAF1BRAFCSF1RDDR1DDR2 | |
| SCHEMBL24399631 | 0.87 | RAF1 (0.64) | RAF1BRAFCSF1RDDR1DDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116096718-A | Aryl amide compound, pharmaceutical composition containing same, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2023-05-09 | — | — | CN | disclosed |
| WO-2022089219-A1 | ARYLAMIDE COMPOUND, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2022-05-05 | — | — | WO | disclosed |