Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 18/20 | 0.49 |
| ▸ | SYK | P43405 | 2/20 | 0.41 |
| ▸ | MAP3K7 | O43318 | 2/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
| ▸ | IRAK1 | P51617 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL357906 | 1.00 | IRAK4 (0.49) | IRAK4SYKMAP3K7AURKAFLT3 | |
| SCHEMBL359686 | 0.84 | IRAK4 (0.50) | IRAK4SYKMAP3K7AURKAFLT3 | |
| SCHEMBL30808248 | 0.84 | IRAK4 (0.50) | IRAK4SYKMAP3K7AURKAFLT3 | |
| SCHEMBL27894609 | 0.81 | IRAK4 (0.46) | IRAK4SYKMAP3K7AURKAFLT3 | |
| SCHEMBL30808056 | 0.79 | IRAK4 (0.49) | IRAK4SYKMAP3K7AURKAFLT3 | |
| SCHEMBL358109 | 0.79 | IRAK4 (0.58) | IRAK4SYKMAP3K7AURKAFLT3 | |
| SCHEMBL19073149 | 0.76 | IRAK4 (0.46) | IRAK4SYKMAP3K7AURKAFLT3 | |
| SCHEMBL15554541 | 0.75 | PTK2 (0.40) | IRAK4SYK | |
| SCHEMBL21371622 | 0.74 | IRAK4 (0.37) | IRAK4SYKMAP3K7AURKAFLT3 | |
| SCHEMBL30808061 | 0.73 | IRAK4 (0.53) | IRAK4SYKMAP3K7AURKAFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119585248-A | Heteroaryl derivatives as DDR inhibitors | 奇斯药制品公司 | 2025-03-07 | — | — | CN | disclosed |
| CN-113039182-B | Inhibitors of YAP/TAZ-TEAD interactions and their use in cancer treatment | 伊文蒂瓦公司 | 2024-02-20 | — | — | CN | disclosed |
| CN-116096718-A | Aryl amide compound, pharmaceutical composition containing same, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2023-05-09 | — | — | CN | disclosed |
| WO-2022089219-A1 | ARYLAMIDE COMPOUND, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2022-05-05 | — | — | WO | disclosed |