Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.47 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21349508 | 1.00 | NR1H2 (0.47) | NR1H2JAK3MEN1ALDH1A1MAPT | |
| SCHEMBL21349507 | 0.87 | NR1H2 (0.46) | NR1H2JAK3MEN1ALDH1A1MAPT | |
| SCHEMBL22990028 | 0.84 | NR1H2 (0.49) | NR1H2JAK3MEN1ALDH1A1MAPT | |
| SCHEMBL21137360 | 0.84 | HPGD (0.41) | MEN1ALDH1A1MAPTKMT2AUSP2 | |
| SCHEMBL14606052 | 0.83 | NR1H2 (0.46) | NR1H2JAK3MEN1ALDH1A1MAPT | |
| SCHEMBL5591325 | 0.83 | NR1H2 (0.46) | NR1H2JAK3MEN1ALDH1A1MAPT | |
| SCHEMBL20585864 | 0.81 | NR1H2 (0.34) | NR1H2MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL20585866 | 0.81 | NR1H2 (0.34) | NR1H2MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL30241681 | 0.80 | KDM5A (0.46) | NR1H2JAK3MEN1ALDH1A1MAPT | |
| SCHEMBL21350249 | 0.80 | NR1H2 (0.50) | NR1H2JAK3MEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3638658-B1 | PHARMACEUTICAL COMPOUNDS | NXERA PHARMA UK LTD (GB) | 2025-10-08 | — | — | EP | disclosed |
| CN-110944992-B | Pharmaceutical compounds | 赫普泰雅治疗有限公司 | 2023-05-16 | — | — | CN | disclosed |
| US-11352342-B2 | Pharmaceutical compounds | HEPTARES THERAPEUTICS LIMITED (GB) | 2022-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11352342-B2 | Pharmaceutical compounds | CHRM1, CHRM2, CHRM4 | NR1H2 234/4885JAK3 3206/4885MEN1 219/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.