Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 6/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | SPHK2 | Q9NRA0 | 3/20 | 0.49 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28741232 | 1.00 | MAPT (0.54) | MAPTNPSR1RXFP1KDM4EALDH1A1 | |
| SCHEMBL28741229 | 1.00 | MAPT (0.54) | MAPTNPSR1RXFP1KDM4EALDH1A1 | |
| SCHEMBL28741184 | 0.89 | MAPT (0.57) | MAPTNPSR1RXFP1KDM4EALDH1A1 | |
| SCHEMBL28741188 | 0.89 | MAPT (0.57) | MAPTNPSR1RXFP1KDM4EALDH1A1 | |
| SCHEMBL29639185 | 0.89 | MAPT (0.57) | MAPTNPSR1RXFP1KDM4EALDH1A1 | |
| SCHEMBL13568949 | 0.85 | MEN1 (0.59) | NPSR1ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL13568927 | 0.84 | MEN1 (0.65) | MAPTNPSR1KDM4EALDH1A1POLB | |
| SCHEMBL29639141 | 0.82 | GAA (0.58) | MAPTKDM4EALDH1A1POLBMEN1 | |
| SCHEMBL28741203 | 0.82 | GAA (0.58) | MAPTKDM4EALDH1A1POLBMEN1 | |
| SCHEMBL15853759 | 0.75 | MEN1 (0.63) | MAPTNPSR1ALDH1A1POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114436978-B | Antifungal compound and application thereof | 中国人民解放军海军军医大学 | 2024-06-18 | — | — | CN | disclosed |
| CN-114436978-A | Antifungal compound and application | 中国人民解放军海军军医大学 | 2022-05-06 | — | — | CN | disclosed |