Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | POLL | Q9UGP5 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14827794 | 0.91 | HTR2C (0.49) | HTR2CKDM4ETSHRDRD2MEN1 | |
| SCHEMBL8125464 | 0.89 | HTR2C (0.47) | HTR2CKDM4ETSHRDRD2MEN1 | |
| SCHEMBL5584542 | 0.88 | HTR2C (0.73) | HTR2CHTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5584541 | 0.88 | HTR2C (0.46) | HTR2CKDM4ETSHRDRD2MEN1 | |
| SCHEMBL28610338 | 0.85 | HTR2C (0.47) | HTR2CKDM4EDRD2MEN1KMT2A | |
| SCHEMBL8115840 | 0.84 | HTR2C (0.43) | HTR2CKDM4ETSHRDRD2HTR1A | |
| SCHEMBL27516251 | 0.81 | HTR2C (0.41) | HTR2CKDM4ETSHRTDP1ALDH1A1 | |
| SCHEMBL27549519 | 0.81 | HTR2C (0.41) | HTR2CKDM4ETSHRTDP1ALDH1A1 | |
| SCHEMBL1515163 | 0.81 | HTR2C (0.75) | HTR2CDRD2MEN1KMT2A | |
| SCHEMBL12964269 | 0.80 | HTR2C (0.53) | HTR2CDRD2MEN1KMT2APOLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114437114-A | Application and preparation of diketopiperazine natural product and derivative and obtained derivative | 中国海洋大学 | 2022-05-06 | — | — | CN | disclosed |