Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.43 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | IDH1 | O75874 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21199933 | 1.00 | RXFP1 (0.50) | RXFP1MAPTLMNAMAPK1HSD17B10 | |
| SCHEMBL29433559 | 0.87 | RXFP1 (0.53) | RXFP1MAPTLMNAMAPK1HSD17B10 | |
| SCHEMBL22670455 | 0.87 | RXFP1 (0.53) | RXFP1MAPTLMNAMAPK1HSD17B10 | |
| SCHEMBL31091996 | 0.81 | RXFP1 (0.52) | RXFP1MAPTLMNAACSS2ALDH1A1 | |
| SCHEMBL29626593 | 0.81 | RXFP1 (0.52) | RXFP1MAPTLMNAACSS2ALDH1A1 | |
| SCHEMBL21200044 | 0.81 | SMN1; SMN2 (0.50) | RXFP1MAPTLMNAMAPK1HSD17B10 | |
| SCHEMBL24027822 | 0.79 | RXFP1 (0.57) | RXFP1MAPTLMNAACSS2ALDH1A1 | |
| SCHEMBL30255999 | 0.79 | RXFP1 (0.57) | RXFP1MAPTLMNAACSS2ALDH1A1 | |
| SCHEMBL30042580 | 0.79 | RXFP1 (0.73) | RXFP1MAPTLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL1013325 | 0.79 | RXFP1 (0.73) | RXFP1MAPTLMNAALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114450271-B | Ureas, amino and substituted heteroaryl compounds for Cbl-b inhibition | 纽力克斯治疗公司 | 2024-09-20 | — | — | CN | disclosed |
| CN-114450271-A | Ureas, amino and substituted heteroaryl compounds for Cbl-b inhibition | 纽力克斯治疗公司 | 2022-05-06 | — | — | CN | disclosed |