SCHEMBL29640152

SCHEMBL29640152

C[C@H](Sc1nncn1C)c1cccc(NC(=O)N2CCN(C)CC2)c1

nearest known ligand 0.67

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CBLB Q13191 20/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22945262 1.00 CBLB (0.67) CBLB
SCHEMBL28741756 1.00 CBLB (0.67) CBLB
SCHEMBL29626619 0.93 CBLB (0.66) CBLB
SCHEMBL28741935 0.93 CBLB (0.66) CBLB
SCHEMBL22945263 0.93 CBLB (0.66) CBLB
SCHEMBL22945258 0.93 CBLB (0.70) CBLB
SCHEMBL22945261 0.93 CBLB (0.70) CBLB
SCHEMBL28741913 0.93 CBLB (0.70) CBLB
SCHEMBL22944839 0.92 CBLB (0.71) CBLB
SCHEMBL28741759 0.92 CBLB (0.71) CBLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114450271-B Ureas, amino and substituted heteroaryl compounds for Cbl-b inhibition 纽力克斯治疗公司 2024-09-20 CN disclosed
CN-114450271-A Ureas, amino and substituted heteroaryl compounds for Cbl-b inhibition 纽力克斯治疗公司 2022-05-06 CN disclosed