SCHEMBL29640175

SCHEMBL29640175

C[C@H](Sc1nncn1C)c1cccc(-n2ncc(-c3ccc(Cl)cc3)n2)c1

nearest known ligand 0.54

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CBLB Q13191 20/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28741832 1.00 CBLB (0.54) CBLB
SCHEMBL22945835 1.00 CBLB (0.54) CBLB
SCHEMBL22945832 0.91 CBLB (0.53) CBLB
SCHEMBL29640107 0.91 CBLB (0.53) CBLB
SCHEMBL28741788 0.91 CBLB (0.53) CBLB
SCHEMBL22945301 0.91 CBLB (0.52) CBLB
SCHEMBL22945291 0.91 CBLB (0.52) CBLB
SCHEMBL28741797 0.91 CBLB (0.52) CBLB
SCHEMBL29626650 0.91 CBLB (0.52) CBLB
SCHEMBL22945410 0.89 CBLB (0.47) CBLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114450271-B Ureas, amino and substituted heteroaryl compounds for Cbl-b inhibition 纽力克斯治疗公司 2024-09-20 CN disclosed
CN-114450271-A Ureas, amino and substituted heteroaryl compounds for Cbl-b inhibition 纽力克斯治疗公司 2022-05-06 CN disclosed