Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 20/20 | 0.71 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.67 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.67 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.67 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.67 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.67 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.67 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.67 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.67 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.67 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23316990 | 1.00 | HDAC6 (0.71) | HDAC6HDAC1HDAC3HDAC2HDAC11 | |
| Trifluoroacetic Acid SCHEMBL20534780 | 0.94 | HDAC6 (0.64) | HDAC6HDAC1HDAC3HDAC2HDAC11 | |
| SCHEMBL29640425 | 0.83 | HDAC6 (1.00) | HDAC6HDAC1HDAC3HDAC2HDAC11 | |
| SCHEMBL23317003 | 0.83 | HDAC6 (1.00) | HDAC6HDAC1HDAC3HDAC2HDAC11 | |
| SCHEMBL30395669 | 0.82 | HDAC6 (1.00) | HDAC6HDAC1HDAC3HDAC2HDAC11 | |
| SCHEMBL20534704 | 0.82 | HDAC6 (1.00) | HDAC6HDAC1HDAC3HDAC2HDAC11 | |
| SCHEMBL23316873 | 0.80 | HDAC6 (1.00) | HDAC6HDAC1HDAC3HDAC2HDAC11 | |
| SCHEMBL23316897 | 0.80 | HDAC6 (0.56) | HDAC6HDAC1HDAC3HDAC2HDAC11 | |
| SCHEMBL29640377 | 0.80 | HDAC6 (0.56) | HDAC6HDAC1HDAC3HDAC2HDAC11 | |
| SCHEMBL20535705 | 0.79 | HDAC6 (0.64) | HDAC6HDAC1HDAC3HDAC2HDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110546140-B | Selective HDAC6 inhibitors | 意大发马克股份公司 | 2023-05-16 | — | — | CN | claimed |
| EP-3562810-B1 | BENZHYDROXAMIC ACID DERIVATIVES AS SELECTIVE HDAC6 INHIBITORS | ITALFARMACO SPA (IT) | 2023-05-03 | — | — | EP | claimed |
| US-11351178-B2 | Selective HDAC6 inhibitors | ITALFARMACO SPA (IT) | 2022-06-07 | — | — | US | claimed |
| CN-110546140-B | Selective HDAC6 inhibitors | 意大发马克股份公司 | 2023-05-16 | — | — | CN | disclosed |
| EP-3562810-B1 | BENZHYDROXAMIC ACID DERIVATIVES AS SELECTIVE HDAC6 INHIBITORS | ITALFARMACO SPA (IT) | 2023-05-03 | — | — | EP | disclosed |
| US-11351178-B2 | Selective HDAC6 inhibitors | ITALFARMACO SPA (IT) | 2022-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11351178-B2 | Selective HDAC6 inhibitors | HDAC6, HDAC1, HDAC3 | HDAC6 1/4885HDAC1 2/4885HDAC3 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.