Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 14/20 | 0.56 |
| ▸ | PDE4A | P27815 | 3/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.50 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16681192 | 1.00 | BRD4 (0.56) | BRD4PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL23104436 | 0.85 | SRD5A1 (0.58) | BRD4DRD2DRD3DRD4 | |
| SCHEMBL16690790 | 0.85 | TNKS (0.41) | BRD4DRD2DRD3DRD4 | |
| SCHEMBL30912528 | 0.82 | BRD4 (0.70) | BRD4PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL30912553 | 0.82 | BRD4 (0.70) | BRD4PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL29640784 | 0.82 | BRD4 (0.56) | BRD4PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL16679752 | 0.82 | BRD4 (0.56) | BRD4PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL23103742 | 0.79 | BRD4 (0.54) | BRD4PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL23107190 | 0.79 | BRD4 (0.54) | BRD4PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL23108852 | 0.77 | BRD4 (0.51) | BRD4PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112218857-B | P300/CBP HAT inhibitors and methods of use thereof | 星座制药公司 | 2023-11-21 | — | — | CN | disclosed |
| CN-114450005-A | Compounds for the treatment of neurological disorders | 星座制药公司 | 2022-05-06 | — | — | CN | disclosed |