Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.49 |
| ▸ | AXL | P30530 | 2/20 | 0.47 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 3/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.43 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | MET | P08581 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3386265 | 1.00 | CYP11B1 (0.49) | CYP11B1CYP11B2AXLCHEK1PIM1 | |
| SCHEMBL12858928 | 0.80 | CYP11B1 (0.57) | CYP11B1CYP11B2CHEK1PIM1MAPK1 | |
| SCHEMBL28363585 | 0.80 | CYP11B1 (0.50) | CYP11B1CYP11B2CHEK1PIM1MAPK1 | |
| SCHEMBL12897481 | 0.79 | FYN (0.57) | CYP11B1CYP11B2CHEK1PIM1MAPK1 | |
| SCHEMBL12594379 | 0.79 | FGFR3 (0.57) | CYP11B1CYP11B2CHEK1PIM1MAPK1 | |
| SCHEMBL15747733 | 0.79 | CYP11B1 (0.49) | CYP11B1CYP11B2AXLCHEK1PIM1 | |
| SCHEMBL16561338 | 0.79 | MKNK1 (0.50) | CYP11B1CYP11B2CHEK1PIM1MAPK1 | |
| SCHEMBL17121370 | 0.78 | CYP11B1 (0.59) | CYP11B1CYP11B2CHEK1PIM1MAPK1 | |
| SCHEMBL31375150 | 0.77 | CCNC (0.58) | AXLCHEK1PIM1MAPK1LRRK2 | |
| SCHEMBL3744510 | 0.77 | AXL (0.51) | AXLPIM1LRRK2KDRMET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112218857-B | P300/CBP HAT inhibitors and methods of use thereof | 星座制药公司 | 2023-11-21 | — | — | CN | disclosed |
| CN-114450005-A | Compounds for the treatment of neurological disorders | 星座制药公司 | 2022-05-06 | — | — | CN | disclosed |