Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 1/20 | 0.47 |
| ▸ | CALCRL | Q16602 | 5/20 | 0.46 |
| ▸ | CMA1 | P23946 | 1/20 | 0.44 |
| ▸ | GRB2 | P62993 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 3/20 | 0.43 |
| ▸ | NTSR2 | O95665 | 1/20 | 0.41 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.41 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | FAP | Q12884 | 1/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30844353 | 0.93 | CALCRL (0.46) | XIAPCALCRLCMA1GRB2ELANE | |
| SCHEMBL30844308 | 0.92 | CMA1 (0.51) | XIAPCALCRLCMA1GRB2ELANE | |
| SCHEMBL30844271 | 0.92 | CALCRL (0.48) | XIAPCALCRLCMA1GRB2ELANE | |
| SCHEMBL29733288 | 0.88 | CALCRL (0.51) | XIAPCALCRLCMA1SLC6A2STAT3 | |
| SCHEMBL23135343 | 0.88 | XIAP (0.53) | XIAPCALCRLGRB2SLC6A2ELANE | |
| SCHEMBL23135342 | 0.88 | XIAP (0.53) | XIAPCALCRLGRB2SLC6A2ELANE | |
| SCHEMBL30844288 | 0.88 | F2 (0.49) | CALCRLCMA1GRB2NTSR2NTSR1 | |
| SCHEMBL30844352 | 0.88 | F2 (0.49) | CALCRLCMA1GRB2NTSR2NTSR1 | |
| SCHEMBL30844246 | 0.88 | F2 (0.49) | CALCRLCMA1GRB2NTSR2NTSR1 | |
| SCHEMBL30844281 | 0.88 | F2 (0.49) | CALCRLCMA1GRB2NTSR2NTSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220409709-A1 | LABYRINTHIN-BASED PEPTIDES FOR CANCER IMMUNOTHERAPIES AND USES THEREOF | LABYRX IMMUNOLOGIC THERAPEUTICS USA LTD (US) | 2022-12-29 | — | — | US | disclosed |
| US-20220089719-A1 | CONSTRUCTS TARGETING LABYRINTHIN OR A PORTION THEREOF AND USES THEREOF | LABYRX IMMUNOLOGIC THERAPEUTICS (USA) LIMITED (US) | 2022-03-24 | — | — | US | disclosed |