Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STIM1 | Q13586 | 8/20 | 0.69 |
| ▸ | ORAI1 | Q96D31 | 8/20 | 0.69 |
| ▸ | ESRRG | P62508 | 2/20 | 0.52 |
| ▸ | IL2 | P60568 | 2/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL721220 | 1.00 | STIM1 (0.69) | STIM1ORAI1ESRRGIL2HDAC3 | |
| SCHEMBL10201561 | 0.93 | STIM1 (0.80) | STIM1ORAI1ESRRGHDAC3HDAC4 | |
| SCHEMBL10201139 | 0.90 | STIM1 (0.70) | STIM1ORAI1ESRRGHDAC3HDAC4 | |
| SCHEMBL10201129 | 0.90 | STIM1 (0.85) | STIM1ORAI1IL2HDAC3HDAC4 | |
| SCHEMBL10201141 | 0.86 | STIM1 (0.82) | STIM1ORAI1ESRRGHDAC3HDAC4 | |
| SCHEMBL10201194 | 0.86 | STIM1 (0.61) | STIM1ORAI1ESRRGHDAC3HDAC4 | |
| SCHEMBL10201140 | 0.86 | STIM1 (0.67) | STIM1ORAI1IL2HDAC3HDAC4 | |
| SCHEMBL10201563 | 0.84 | STIM1 (0.62) | STIM1ORAI1ESRRGHDAC3HDAC4 | |
| SCHEMBL10201116 | 0.84 | STIM1 (0.67) | STIM1ORAI1IL2HDAC3HDAC4 | |
| SCHEMBL10201127 | 0.84 | STIM1 (0.65) | STIM1ORAI1ESRRGHDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114591311-A | Compounds that modulate intracellular calcium | 钙医学公司 | 2022-06-07 | — | — | CN | disclosed |