Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STIM1 | Q13586 | 5/20 | 0.71 |
| ▸ | ORAI1 | Q96D31 | 5/20 | 0.71 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.58 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.58 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.58 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.58 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.58 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.58 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 5/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | IL2 | P60568 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10201265 | 1.00 | STIM1 (0.71) | STIM1ORAI1HDAC3HDAC4HDAC1 | |
| SCHEMBL10256229 | 0.88 | STIM1 (0.61) | STIM1ORAI1HDAC3HDAC4HDAC1 | |
| SCHEMBL10201266 | 0.88 | STIM1 (0.83) | STIM1ORAI1HDAC3HDAC4HDAC1 | |
| SCHEMBL10201644 | 0.87 | STIM1 (0.77) | STIM1ORAI1HDAC3HDAC4HDAC1 | |
| SCHEMBL14999212 | 0.86 | STIM1 (0.55) | STIM1ORAI1RAB9AKDM4EALDH1A1 | |
| SCHEMBL10201282 | 0.84 | STIM1 (0.54) | STIM1ORAI1HDAC3HDAC4HDAC1 | |
| SCHEMBL10201030 | 0.84 | STIM1 (0.72) | STIM1ORAI1HDAC3HDAC4HDAC1 | |
| SCHEMBL10201652 | 0.83 | STIM1 (1.00) | STIM1ORAI1HDAC3HDAC4HDAC1 | |
| SCHEMBL5623668 | 0.82 | STIM1 (0.69) | STIM1ORAI1HDAC3HDAC4HDAC1 | |
| SCHEMBL16010157 | 0.80 | CRACR2A (0.48) | STIM1ORAI1HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114591311-A | Compounds that modulate intracellular calcium | 钙医学公司 | 2022-06-07 | — | — | CN | disclosed |