SCHEMBL29642695

SCHEMBL29642695

O=C=Nc1ccc2cccc(N=C=O)c2c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 6/20 0.49
TRPA1 O75762 1/20 0.49
TDP1 Q9NUW8 3/20 0.43
MAPK1 P28482 1/20 0.43
CYP1A2 P05177 4/20 0.42
ALDH1A1 P00352 3/20 0.42
HPGD P15428 3/20 0.42
HSD17B10 Q99714 2/20 0.42
ABCB11 O95342 1/20 0.42
NR3C1 P04150 1/20 0.42
ADRA2A P08913 1/20 0.42
ADORA3 P0DMS8 1/20 0.42
ALOX15 P16050 1/20 0.42
ADRA2C P18825 1/20 0.42
MAOA P21397 1/20 0.42
DRD1 P21728 1/20 0.42
SLC6A4 P31645 1/20 0.42
HTR2B P41595 1/20 0.42
CCR2 P41597 1/20 0.42
TSHR P16473 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL662710 1.00 CYP3A4 (0.49) CYP3A4TRPA1TDP1MAPK1CYP1A2
SCHEMBL9231657 0.88 CYP3A4 (0.45) CYP3A4TRPA1TDP1MAPK1CYP1A2
SCHEMBL543165 0.86 CYP3A4 (0.49) CYP3A4TRPA1TDP1MAPK1CYP1A2
SCHEMBL29642626 0.86 CYP3A4 (0.49) CYP3A4TRPA1TDP1MAPK1CYP1A2
SCHEMBL29642545 0.86 CYP3A4 (0.49) CYP3A4TRPA1TDP1MAPK1CYP1A2
SCHEMBL9229488 0.83 CYP3A4 (0.54) CYP3A4TRPA1TDP1MAPK1CYP1A2
SCHEMBL6821492 0.81 MCL1 (0.45) CYP3A4TDP1CYP1A2ALDH1A1HPGD
SCHEMBL542827 0.80 CYP3A4 (0.55) CYP3A4TRPA1TDP1MAPK1CYP1A2
SCHEMBL5573537 0.79 CYP3A4 (0.54) CYP3A4TRPA1TDP1MAPK1CYP1A2
Alpha-Naphthylisocyanate SCHEMBL29400034 0.79 CYP1A2 (0.64) CYP3A4TDP1CYP1A2ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110997851-B Allyl-functionalized urethane oligomers and related compositions for coatings and adhesives 阿科玛法国公司 2022-06-07 CN disclosed