Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 20/20 | 0.71 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.65 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.65 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19469593 | 1.00 | CFTR (0.71) | CFTRGABRA1TMEM97SIGMAR1 | |
| SCHEMBL19469597 | 1.00 | CFTR (0.71) | CFTRGABRA1TMEM97SIGMAR1 | |
| SCHEMBL19469596 | 1.00 | CFTR (0.71) | CFTRGABRA1TMEM97SIGMAR1 | |
| SCHEMBL17709141 | 0.95 | CFTR (0.75) | CFTRGABRA1TMEM97SIGMAR1 | |
| SCHEMBL17709089 | 0.95 | CFTR (0.75) | CFTRGABRA1TMEM97SIGMAR1 | |
| SCHEMBL17708735 | 0.92 | CFTR (0.68) | CFTRGABRA1TMEM97SIGMAR1 | |
| SCHEMBL29642784 | 0.92 | CFTR (0.68) | CFTRGABRA1TMEM97SIGMAR1 | |
| SCHEMBL19469577 | 0.92 | CFTR (0.68) | CFTRGABRA1TMEM97SIGMAR1 | |
| SCHEMBL19469575 | 0.92 | CFTR (0.68) | CFTRGABRA1TMEM97SIGMAR1 | |
| SCHEMBL19469579 | 0.92 | CFTR (0.68) | CFTRGABRA1TMEM97SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114671864-B | Heteroaryl substituted pyridines and methods of use | 艾伯维公司 | 2025-04-08 | — | — | CN | disclosed |
| WO-2022150173-A1 | MODULATORS OF THE CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR PROTEIN AND METHODS OF USE | AbbVie Global Enterprises Ltd. (BM) | 2022-07-14 | — | — | WO | disclosed |
| CN-114671864-A | Heteroaryl substituted pyridines and methods of use | 艾伯维公司 | 2022-06-28 | — | — | CN | disclosed |
| CN-109311864-B | Heteroaryl substituted pyridines and methods of use | 艾伯维公司 | 2022-05-10 | — | — | CN | disclosed |