Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | TLK2 | Q86UE8 | 1/20 | 0.53 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.49 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.48 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.48 |
| ▸ | AHR | P35869 | 1/20 | 0.47 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.47 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.47 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.47 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.47 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10365651 | 0.87 | CRBN (0.64) | MEN1KMT2ACRBNHDAC3HDAC4 | |
| SCHEMBL2547584 | 0.86 | SMYD3 (0.53) | SMYD3TLK2CRBNLRRK2MAPKAPK2 | |
| SCHEMBL154971 | 0.85 | SMYD3 (0.60) | SMYD3TLK2CRBNLRRK2AHR | |
| SCHEMBL155039 | 0.83 | SMYD3 (0.53) | SMYD3TLK2GRIN2DGRIN3BGRIN1 | |
| SCHEMBL29642948 | 0.83 | SMYD3 (0.61) | SMYD3TLK2CRBNLRRK2MAPKAPK2 | |
| SCHEMBL578342 | 0.83 | SMYD3 (0.61) | SMYD3TLK2CRBNLRRK2MAPKAPK2 | |
| SCHEMBL22425051 | 0.82 | NPC1 (0.59) | SMYD3MEN1KMT2ATLK2 | |
| SCHEMBL3171463 | 0.82 | SMYD3 (0.60) | SMYD3TLK2LRRK2AHRGRIN2D | |
| SCHEMBL5728126 | 0.82 | SMYD3 (0.64) | SMYD3TLK2LRRK2MAPKAPK2AHR | |
| SCHEMBL4405727 | 0.81 | CRBN (0.65) | SMYD3KMT2ATLK2CRBNLRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111285872-B | Indole-2-ketone derivative and preparation method and application thereof | 北京志健金瑞生物医药科技有限公司 | 2022-05-17 | — | — | CN | disclosed |