SCHEMBL2964298

SCHEMBL2964298

O=C(O)[C@H]1NCCC[C@H]1O

nearest known ligand 0.63

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.63
BLM P54132 1/20 0.63
KMT2A Q03164 1/20 0.63
ARG1 P05089 5/20 0.50
SLC1A2 P43004 1/20 0.50
SLC6A1 P30531 2/20 0.39
SLC6A11 P48066 1/20 0.39
TSHR P16473 1/20 0.39
LMNA P02545 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
SLC6A13 Q9NSD5 1/20 0.39
ARG2 P78540 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL351910 1.00 MEN1 (0.63) MEN1BLMKMT2AARG1SLC1A2
SCHEMBL2964302 1.00 MEN1 (0.63) MEN1BLMKMT2AARG1SLC1A2
SCHEMBL17943259 1.00 MEN1 (0.63) MEN1BLMKMT2AARG1SLC1A2
SCHEMBL3260294 1.00 MEN1 (0.63) MEN1BLMKMT2AARG1SLC1A2
SCHEMBL12909421 1.00 MEN1 (0.63) MEN1BLMKMT2AARG1SLC1A2
Hydrochloric Acid SCHEMBL28578650 0.98 MEN1 (0.61) MEN1BLMKMT2AARG1SLC1A2
SCHEMBL18561419 0.91 MEN1 (0.53) MEN1BLMKMT2AARG1SLC1A2
SCHEMBL1364961 0.86
SCHEMBL114870 0.86
SCHEMBL2025245 0.86

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12415992-B2 Dioxygenase mutants and use thereof in synthesizing (2S,3R)-3-hydroxypipecolic acid JIANGNAN UNIVERSITY (CN) 2025-09-16 US claimed
US-20250179542-A1 BIOCATALYSTS AND METHODS FOR HYDROXYLATION OF CHEMICAL COMPOUNDS CODEXIS INC (US) 2025-06-05 US claimed
US-20250171748-A1 DIOXYGENASE MUTANTS AND USE THEREOF IN SYNTHESIZING (2S,3R)-3-HYDROXYPIPECOLIC ACID JIANGNAN UNIVERSITY (CN) 2025-05-29 US claimed
US-12247234-B2 Biocatalysts and methods for hydroxylation of chemical compounds CODEXIS, INC. (US) 2025-03-11 US claimed
US-20230227875-A1 BIOCATALYSTS AND METHODS FOR HYDROXYLATION OF CHEMICAL COMPOUNDS INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT 2023-07-20 US claimed
US-11549132-B2 Biocatalysts and methods for hydroxylation of chemical compounds CODEXIS, INC. (US) 2023-01-10 US claimed
CN-107699548-B Biocatalysts and methods for hydroxylation of chemical compounds 科德克希思公司 2021-10-22 CN claimed
US-20210230654-A1 BIOCATALYSTS AND METHODS FOR HYDROXYLATION OF CHEMICAL COMPOUNDS INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT 2021-07-29 US claimed
US-10995349-B2 Engineered proline hydroxylase polypeptides and methods CODEXIS, INC. (US) 2021-05-04 US claimed
US-20200325510-A1 BIOCATALYSTS AND METHODS FOR HYDROXYLATION OF CHEMICAL COMPOUNDS INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT 2020-10-15 US claimed
US-10731189-B2 Engineered proline hydroxylase polynucleotides and methods CODEXIS, INC. (US) 2020-08-04 US claimed
US-20190323046-A1 BIOCATALYSTS AND METHODS FOR HYDROXYLATION OF CHEMICAL COMPOUNDS INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT 2019-10-24 US claimed
EP-2847327-B1 BIOCATALYSTS AND METHODS FOR HYDROXYLATION OF CHEMICAL COMPOUNDS CODEXIS INC (US) 2018-12-26 EP claimed
US-9790527-B2 Engineered proline hydroxylase polypeptides CODEXIS, INC. (US) 2017-10-17 US claimed
US-20150118719-A1 BIOCATALYSTS AND METHODS FOR HYDROXYLATION OF CHEMICAL COMPOUNDS INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT 2015-04-30 US claimed
EP-2847327-A2 BIOCATALYSTS AND METHODS FOR HYDROXYLATION OF CHEMICAL COMPOUNDS Codexis, Inc. (US) 2015-03-18 EP claimed
WO-2013169725-A2 BIOCATALYSTS AND METHODS FOR HYDROXYLATION OF CHEMICAL COMPOUNDS CODEXIS, INC. (US) 2013-11-14 WO claimed
US-12415992-B2 Dioxygenase mutants and use thereof in synthesizing (2S,3R)-3-hydroxypipecolic acid JIANGNAN UNIVERSITY (CN) 2025-09-16 US disclosed
US-6670386-B2 For therapy of nuclear hormone receptor-associated conditions, such as age related diseases, for example sarcopenia BRISTOL-MYERS SQUIBB COMPANY 2003-12-30 US disclosed
US-20030055094-A1 Bicyclic modulators of androgen receptor function BRISTOL-MYERS SQUIBB COMPANY 2003-03-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030055094-A1 Bicyclic modulators of androgen receptor function AR, NR5A1, ESRRA MEN1 3920/4885BLM 3884/4885KMT2A 2827/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.