SCHEMBL29643200

SCHEMBL29643200

Clc1ccc(-c2ccc3sc4cccc(-c5nc(-c6ccccc6)nc(-c6ccccc6)n5)c4c3c2)cc1

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
EGFR P00533 1/20 0.38
PIM3 Q86V86 1/20 0.38
DPP4 P27487 1/20 0.37
CYP1A2 P05177 1/20 0.37
CTRC Q99895 1/20 0.36
MAOB P27338 1/20 0.36
KDM4E B2RXH2 1/20 0.36
LIMK1 P53667 1/20 0.36
NR1H2 P55055 2/20 0.35
NR1H3 Q13133 2/20 0.35
NPC1 O15118 1/20 0.35
MAPK1 P28482 1/20 0.35
HTT P42858 1/20 0.35
RAB9A P51151 1/20 0.35
CNR1 P21554 1/20 0.35
PDE5A O76074 1/20 0.34
ABCG2 Q9UNQ0 1/20 0.34
ROCK1 Q13464 1/20 0.34
MAP4K4 O95819 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21930661 1.00 EGFR (0.38) EGFRPIM3DPP4CYP1A2CTRC
SCHEMBL20391688 0.98 EGFR (0.37) EGFRPIM3DPP4CYP1A2CTRC
SCHEMBL19802135 0.94 PIM3 (0.41) PIM3KDM4ELIMK1ROCK1
SCHEMBL20391998 0.94 PIM3 (0.41) PIM3KDM4ELIMK1ROCK1
SCHEMBL19802119 0.94 PIM3 (0.41) PIM3KDM4ELIMK1ROCK1
SCHEMBL24216417 0.94 PIM3 (0.41) PIM3KDM4ELIMK1ROCK1
SCHEMBL22329241 0.94 PIM3 (0.41) PIM3KDM4ELIMK1ROCK1
SCHEMBL22140779 0.94 PIM3 (0.41) PIM3KDM4ELIMK1ROCK1
SCHEMBL24231220 0.94 PIM3 (0.41) PIM3KDM4ELIMK1ROCK1
SCHEMBL19802544 0.94 PIM3 (0.41) PIM3KDM4ELIMK1ROCK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110431136-B Material for organic electroluminescent device 默克专利有限公司 2023-05-23 CN disclosed
EP-3596066-B1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2022-05-18 EP disclosed