Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.80 |
| ▸ | HPGD | P15428 | 2/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.79 |
| ▸ | CNR2 | P34972 | 13/20 | 0.67 |
| ▸ | RORC | P51449 | 1/20 | 0.58 |
| ▸ | CNR1 | P21554 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28266234 | 1.00 | NPC1 (0.80) | NPC1HPGDALDH1A1CNR2RORC | |
| SCHEMBL16098831 | 0.88 | NPC1 (0.67) | NPC1HPGDALDH1A1CNR2RORC | |
| SCHEMBL16098077 | 0.88 | HPGD (1.00) | NPC1HPGDALDH1A1CNR2RORC | |
| SCHEMBL2774463 | 0.88 | HPGD (0.79) | NPC1HPGDALDH1A1CNR2RORC | |
| SCHEMBL7979578 | 0.88 | KDM4E (0.68) | NPC1HPGDALDH1A1RORCKDM4E | |
| SCHEMBL30150496 | 0.88 | KDM4E (0.68) | NPC1HPGDALDH1A1RORCKDM4E | |
| SCHEMBL16099093 | 0.87 | HPGD (0.73) | NPC1HPGDALDH1A1CNR2RORC | |
| SCHEMBL12784987 | 0.87 | HPGD (0.77) | NPC1HPGDALDH1A1CNR2RORC | |
| SCHEMBL16120023 | 0.86 | NPC1 (0.62) | NPC1HPGDALDH1A1CNR2RORC | |
| SCHEMBL17461866 | 0.86 | NPC1 (0.64) | NPC1HPGDALDH1A1CNR2RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109206360-B | Carbazole amide derivative or salt thereof, and preparation method and application thereof | 复旦大学 | 2022-05-17 | — | — | CN | disclosed |