Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.67 |
| ▸ | MEN1 | O00255 | 5/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.67 |
| ▸ | HTT | P42858 | 4/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.67 |
| ▸ | HPGD | P15428 | 2/20 | 0.67 |
| ▸ | HBB | P68871 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 6/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | PGR | P06401 | 1/20 | 0.55 |
| ▸ | RORA | P35398 | 1/20 | 0.55 |
| ▸ | RORC | P51449 | 1/20 | 0.55 |
| ▸ | RORB | Q92753 | 1/20 | 0.55 |
| ▸ | SRC | P12931 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL156150 | 1.00 | MAPT (0.67) | MAPTKDM4EMEN1KMT2AHTT | |
| SCHEMBL12582803 | 0.93 | MAPT (0.59) | MAPTKDM4EMEN1KMT2AHTT | |
| SCHEMBL1611235 | 0.90 | KDM4E (0.52) | MAPTKDM4EMEN1KMT2AHTT | |
| SCHEMBL13899929 | 0.89 | MAPT (0.55) | MAPTKDM4EMEN1KMT2AHTT | |
| SCHEMBL9119652 | 0.89 | MAPT (0.57) | MAPTKDM4EMEN1KMT2AHTT | |
| SCHEMBL14728190 | 0.89 | MAPT (0.54) | MAPTKDM4EMEN1KMT2AHTT | |
| SCHEMBL14114969 | 0.87 | CYP1A2 (0.65) | MAPTKDM4EMEN1KMT2AHTT | |
| SCHEMBL13921743 | 0.86 | MAPT (0.59) | MAPTKDM4EMEN1KMT2AHTT | |
| SCHEMBL15458667 | 0.86 | HPGD (0.61) | MAPTKDM4EMEN1KMT2AHTT | |
| SCHEMBL19271261 | 0.84 | MAPT (0.49) | MAPTKDM4EMEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109206360-B | Carbazole amide derivative or salt thereof, and preparation method and application thereof | 复旦大学 | 2022-05-17 | — | — | CN | disclosed |