Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 20/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22890265 | 1.00 | LRRK2 (0.53) | LRRK2 | |
| SCHEMBL29644045 | 0.89 | LRRK2 (0.56) | LRRK2 | |
| SCHEMBL22890810 | 0.89 | LRRK2 (0.56) | LRRK2 | |
| SCHEMBL22890842 | 0.89 | LRRK2 (0.57) | LRRK2 | |
| SCHEMBL29644098 | 0.89 | LRRK2 (0.57) | LRRK2 | |
| SCHEMBL22890782 | 0.88 | LRRK2 (0.53) | LRRK2 | |
| SCHEMBL29643975 | 0.88 | LRRK2 (0.53) | LRRK2 | |
| SCHEMBL22890694 | 0.87 | LRRK2 (0.55) | LRRK2 | |
| SCHEMBL29644035 | 0.87 | LRRK2 (0.55) | LRRK2 | |
| SCHEMBL22890590 | 0.86 | LRRK2 (0.57) | LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3997081-A1 | INDAZOLES AND AZAINDAZOLES AS LRRK2 INHIBITORS | Escape Bio, Inc. (US) | 2022-05-18 | — | — | EP | disclosed |