Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22890316 | 1.00 | LRRK2 (1.00) | LRRK2 | |
| SCHEMBL29644048 | 0.92 | LRRK2 (1.00) | LRRK2 | |
| SCHEMBL22890058 | 0.92 | LRRK2 (1.00) | LRRK2 | |
| SCHEMBL22890076 | 0.88 | LRRK2 (1.00) | LRRK2 | |
| SCHEMBL29644061 | 0.88 | LRRK2 (1.00) | LRRK2 | |
| SCHEMBL22890129 | 0.86 | LRRK2 (1.00) | LRRK2 | |
| SCHEMBL29644083 | 0.86 | LRRK2 (1.00) | LRRK2 | |
| SCHEMBL22890355 | 0.86 | LRRK2 (1.00) | LRRK2 | |
| SCHEMBL22890060 | 0.85 | LRRK2 (1.00) | LRRK2 | |
| SCHEMBL29643894 | 0.85 | LRRK2 (1.00) | LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3997081-A1 | INDAZOLES AND AZAINDAZOLES AS LRRK2 INHIBITORS | Escape Bio, Inc. (US) | 2022-05-18 | — | — | EP | disclosed |