Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 11/20 | 0.43 |
| ▸ | ACHE | P22303 | 7/20 | 0.43 |
| ▸ | CNR1 | P21554 | 6/20 | 0.43 |
| ▸ | F2RL3 | Q96RI0 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2144668 | 0.92 | F2RL3 (0.37) | CNR2ACHECNR1F2RL3MAPT | |
| SCHEMBL22445989 | 0.85 | CNR2 (0.48) | CNR2ACHECNR1F2RL3MAPT | |
| SCHEMBL29644071 | 0.84 | CNR2 (0.45) | CNR2ACHECNR1F2RL3MAPT | |
| SCHEMBL30183407 | 0.84 | CNR2 (0.45) | CNR2ACHECNR1F2RL3MAPT | |
| SCHEMBL3517141 | 0.84 | CNR2 (0.45) | CNR2ACHECNR1F2RL3MAPT | |
| SCHEMBL2470918 | 0.84 | CNR2 (0.45) | CNR2ACHECNR1F2RL3MAPT | |
| SCHEMBL2144082 | 0.82 | ELANE (0.41) | CNR2ACHECNR1F2RL3MAPT | |
| SCHEMBL3516322 | 0.82 | CNR2 (0.43) | CNR2ACHECNR1F2RL3MAPT | |
| SCHEMBL29643957 | 0.81 | CNR2 (0.41) | CNR2ACHECNR1F2RL3MAPT | |
| SCHEMBL29643912 | 0.81 | CNR1 (0.36) | CNR2ACHECNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3997081-A1 | INDAZOLES AND AZAINDAZOLES AS LRRK2 INHIBITORS | Escape Bio, Inc. (US) | 2022-05-18 | — | — | EP | disclosed |