Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 11/20 | 0.57 |
| ▸ | RAB9A | P51151 | 11/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.57 |
| ▸ | LMNA | P02545 | 5/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.52 |
| ▸ | RELA | Q04206 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | GFER | P55789 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28738947 | 1.00 | NPC1 (0.57) | NPC1RAB9ASMN1; SMN2LMNAKDM4E | |
| SCHEMBL28895800 | 0.94 | NPC1 (0.60) | NPC1RAB9ASMN1; SMN2LMNAKDM4E | |
| SCHEMBL30021559 | 0.94 | NPC1 (0.60) | NPC1RAB9ASMN1; SMN2LMNAKDM4E | |
| SCHEMBL30605183 | 0.87 | NPC1 (0.69) | NPC1RAB9ASMN1; SMN2LMNAKDM4E | |
| SCHEMBL18661251 | 0.86 | MAPT (0.66) | NPC1RAB9ASMN1; SMN2LMNAKDM4E | |
| SCHEMBL5608972 | 0.83 | NPC1 (0.73) | NPC1RAB9ASMN1; SMN2LMNAKDM4E | |
| SCHEMBL13972841 | 0.82 | NPC1 (0.67) | NPC1RAB9ASMN1; SMN2LMNAKDM4E | |
| SCHEMBL11395129 | 0.81 | MAPT (0.75) | NPC1RAB9ASMN1; SMN2LMNAKDM4E | |
| SCHEMBL17933567 | 0.79 | MAPT (0.72) | NPC1RAB9ASMN1; SMN2LMNAKDM4E | |
| SCHEMBL29644215 | 0.79 | NPC1 (0.58) | NPC1RAB9ASMN1; SMN2LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114507246-B | Benzimidazole substituted amino phenol oxygen zinc halide, and preparation method and application thereof | 华东理工大学 | 2024-09-24 | — | — | CN | disclosed |
| CN-109879810-B | Imidazole ring substituted aminophenol oxygen radical zinc complex and preparation method and application thereof | 华东理工大学 | 2022-10-28 | — | — | CN | disclosed |
| CN-114507246-A | Benzimidazole substituted aminophenoxy zinc halide and preparation method and application thereof | 华东理工大学 | 2022-05-17 | — | — | CN | disclosed |