SCHEMBL29644502

SCHEMBL29644502

Cc1cc(NCc2cccs2)c2nc(C)c(-c3ccc4c(c3)c(C)nn4C)n2n1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PI4KB Q9UBF8 3/20 0.43
KDM4E B2RXH2 5/20 0.41
SMN1; SMN2 Q16637 4/20 0.41
ALDH1A1 P00352 4/20 0.41
RAB9A P51151 3/20 0.41
NPC1 O15118 2/20 0.41
HTT P42858 2/20 0.41
CLK4 Q9HAZ1 5/20 0.40
DYRK1A Q13627 1/20 0.40
TSHR P16473 3/20 0.39
BRD4 O60885 1/20 0.38
HPGD P15428 2/20 0.38
CYP1A2 P05177 3/20 0.37
CYP3A4 P08684 3/20 0.37
CYP2D6 P10635 3/20 0.37
CYP2C19 P33261 3/20 0.37
LMNA P02545 2/20 0.37
APEX1 P27695 2/20 0.37
CASP7 P55210 2/20 0.37
USP2 O75604 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21628167 1.00 PI4KB (0.43) PI4KBKDM4ESMN1; SMN2ALDH1A1RAB9A
SCHEMBL29644484 0.84 PI4KB (0.49) PI4KB
SCHEMBL21628161 0.84 PI4KB (0.49) PI4KB
SCHEMBL23023809 0.83 PI4KB (0.37) PI4KBCLK4DYRK1ASMPD3
SCHEMBL21628164 0.81 PI4KB (0.45) PI4KBSMN1; SMN2RAB9ANPC1
SCHEMBL20528846 0.80 PI4KB (0.42) PI4KBSMPD3
SCHEMBL29644511 0.80 PI4KB (0.42) PI4KBSMPD3
SCHEMBL20528858 0.80 PI4KB (0.54) PI4KBKDM4ESMN1; SMN2ALDH1A1RAB9A
SCHEMBL29644496 0.80 PI4KB (0.54) PI4KBKDM4ESMN1; SMN2ALDH1A1RAB9A
SCHEMBL21628168 0.79 PI4KB (0.46) PI4KB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4676485-A1 COMPOUND AND FORMULATION FOR SYSTEMIC THERAPY BY ORAL TRANSMUCOSAL ADMINISTRATION CUROVIR AB (SE) 2026-01-14 EP claimed
WO-2024184442-A1 COMPOUND AND FORMULATION FOR SYSTEMIC THERAPY BY ORAL TRANSMUCOSAL ADMINISTRATION CUROVIR AB (SE) 2024-09-12 WO claimed
EP-4028131-A1 HETEROAROMATIC COMPOUNDS USEFUL IN THERAPY CUROVIR AB (SE) 2022-07-20 EP claimed
CN-110520424-B Heteroaromatic compounds for therapy 库洛维公司 2022-06-21 CN claimed
EP-4676485-A1 COMPOUND AND FORMULATION FOR SYSTEMIC THERAPY BY ORAL TRANSMUCOSAL ADMINISTRATION CUROVIR AB (SE) 2026-01-14 EP disclosed
WO-2024184442-A1 COMPOUND AND FORMULATION FOR SYSTEMIC THERAPY BY ORAL TRANSMUCOSAL ADMINISTRATION CUROVIR AB (SE) 2024-09-12 WO disclosed