Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 18/20 | 0.72 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.72 |
| ▸ | F2 | P00734 | 1/20 | 0.72 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL296451 | 1.00 | F10 (0.72) | F10KCNH2F2KLKB1 | |
| SCHEMBL891007 | 0.91 | KCNH2 (0.66) | F10KCNH2F2KLKB1 | |
| SCHEMBL21430146 | 0.88 | F10 (0.75) | F10KCNH2F2KLKB1 | |
| SCHEMBL12503549 | 0.87 | F10 (0.55) | F10KCNH2F2KLKB1 | |
| SCHEMBL6109439 | 0.85 | F10 (0.75) | F10KCNH2F2KLKB1 | |
| SCHEMBL12132941 | 0.85 | F10 (0.78) | F10KCNH2F2KLKB1 | |
| SCHEMBL14996400 | 0.85 | F10 (0.78) | F10KCNH2F2KLKB1 | |
| Betrixaban SCHEMBL29374026 | 0.84 | F10 (1.00) | F10KCNH2F2 | |
| SCHEMBL2607614 | 0.84 | F10 (0.80) | F10KCNH2F2KLKB1 | |
| Betrixaban SCHEMBL158591 | 0.84 | F10 (1.00) | F10KCNH2F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1948608-B1 | PHARMACEUTICAL SALTS AND POLYMORPHS OF N-(5-CHLORO-2-PYRIDINYL)-2-[[4-[(DIMETHYLAMINO)IMINOMETHYL]BENZOYL]AMINO]-5-METHOXY-BENZAMIDE , A FACTOR XA INHIBITOR | MILLENNIUM PHARM INC (US) | 2012-03-14 | — | — | EP | disclosed |
| EP-1948608-A2 | PHARMACEUTICAL SALTS AND POLYMORPHS OF N-(5-CHLORO-2-PYRIDINYL)-2-[[4-[(DIMETHYLAMINO)IMINOMETHYL]BENZOYL]AMINO]-5-METHOXY-BENZAMIDE , A FACTOR XA INHIBITOR | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2008-07-30 | — | — | EP | disclosed |