Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 14/20 | 0.70 |
| ▸ | GSK3B | P49841 | 2/20 | 0.60 |
| ▸ | KCNN3 | Q9UGI6 | 4/20 | 0.53 |
| ▸ | KCNN1 | Q92952 | 2/20 | 0.53 |
| ▸ | KCNN2 | Q9H2S1 | 2/20 | 0.53 |
| ▸ | CCNE1 | P24864 | 5/20 | 0.53 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.49 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12953673 | 1.00 | CDK2 (0.70) | CDK2GSK3BKCNN3KCNN1KCNN2 | |
| SCHEMBL13304765 | 0.84 | CDK2 (0.77) | CDK2GSK3BCCNE1CCNA2CCNA1 | |
| SCHEMBL13998577 | 0.83 | GSK3B (0.57) | CDK2GSK3BCCNE1CCNA2CCNA1 | |
| SCHEMBL12953328 | 0.82 | CDK2 (1.00) | CDK2GSK3BCCNE1CCNA2CCNA1 | |
| SCHEMBL12953495 | 0.82 | CDK2 (1.00) | CDK2GSK3BCCNE1CCNA2CCNA1 | |
| SCHEMBL12953444 | 0.82 | CDK2 (0.62) | CDK2GSK3BKCNN3KCNN1KCNN2 | |
| SCHEMBL12953671 | 0.81 | CDK2 (0.76) | CDK2GSK3BCCNE1CCNA2CCNA1 | |
| SCHEMBL14418795 | 0.78 | CDK2 (0.58) | CDK2GSK3BKCNN3KCNN1KCNN2 | |
| SCHEMBL14565183 | 0.76 | CDK2 (0.72) | CDK2GSK3BCCNE1CCNA2CCNA1 | |
| SCHEMBL5454018 | 0.76 | CDK2 (0.67) | CDK2KCNN3KCNN1KCNN2CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4256086-A1 | METHODS AND SYSTEMS OF STRATIFYING INFLAMMATORY DISEASE PATIENTS | Cedars-Sinai Medical Center (US) | 2023-10-11 | — | — | EP | disclosed |
| EP-4162076-A1 | TREATMENTS FOR A SUB-POPULATION OF INFLAMMATORY BOWEL DISEASE PATIENTS | Cedars-Sinai Medical Center (US) | 2023-04-12 | — | — | EP | disclosed |
| WO-2022119842-A1 | METHODS AND SYSTEMS OF STRATIFYING INFLAMMATORY DISEASE PATIENTS | CEDARS-SINAI MEDICAL CENTER (US) | 2022-06-09 | — | — | WO | disclosed |