Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 3/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.34 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.33 |
| ▸ | TNF | P01375 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | LITAF | Q99732 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.32 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22979137 | 1.00 | PIM1 (0.35) | PIM1ADORA2AADORA1PIM3PIM2 | |
| SCHEMBL29648877 | 0.91 | PIM1 (0.35) | PIM1ADORA2AADORA1PIM3PIM2 | |
| SCHEMBL22978999 | 0.91 | PIM1 (0.35) | PIM1ADORA2AADORA1PIM3PIM2 | |
| SCHEMBL22988433 | 0.91 | PIM1 (0.35) | PIM1ADORA2AADORA1PIM3PIM2 | |
| SCHEMBL31149998 | 0.91 | PIM1 (0.35) | PIM1ADORA2AADORA1PIM3PIM2 | |
| SCHEMBL29645871 | 0.91 | ADORA2A (0.37) | ADORA2AADORA1MKNK1MKNK2ADORA3 | |
| SCHEMBL22980138 | 0.91 | ADORA2A (0.37) | ADORA2AADORA1MKNK1MKNK2ADORA3 | |
| SCHEMBL22980792 | 0.90 | ADORA2A (0.39) | ADORA2AADORA1TNFLITAFHSP90AB1 | |
| SCHEMBL22979685 | 0.90 | PIM1 (0.34) | PIM1ADORA2AADORA1PIM3PIM2 | |
| SCHEMBL22979003 | 0.89 | PIM1 (0.34) | PIM1ADORA2AADORA1PIM3PIM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-B | [1,2,4] Triazolo [1,5-C ] quinazolin-5-amine | 拜耳股份有限公司 | 2024-09-10 | — | — | CN | claimed |
| EP-4013508-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | Bayer Aktiengesellschaft (DE) | 2022-06-22 | — | — | EP | claimed |
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | claimed |