Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.30 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.30 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22979782 | 1.00 | JAK2 (0.33) | JAK2TYK2PIK3CDADORA2AADORA1 | |
| SCHEMBL25118922 | 1.00 | JAK2 (0.33) | JAK2TYK2PIK3CDADORA2AADORA1 | |
| SCHEMBL22979260 | 0.93 | JAK2 (0.37) | JAK2TYK2ADORA2AADORA1LRRK2 | |
| SCHEMBL29645651 | 0.90 | JAK2 (0.33) | JAK2TYK2PIK3CDLRRK2 | |
| SCHEMBL22979209 | 0.90 | JAK2 (0.33) | JAK2TYK2PIK3CDLRRK2 | |
| SCHEMBL22979950 | 0.90 | CREBBP (0.35) | PIK3CDADORA2AADORA1LRRK2 | |
| SCHEMBL22979216 | 0.89 | ADORA2A (0.33) | ADORA2AADORA1MKNK1MKNK2 | |
| SCHEMBL22979232 | 0.88 | KDM5A (0.36) | ADORA2AADORA1SCN9AMKNK1MKNK2 | |
| SCHEMBL22978964 | 0.88 | ADORA2A (0.36) | ADORA2AADORA1 | |
| SCHEMBL22979051 | 0.88 | KDM5A (0.38) | JAK2ADORA2AADORA1MKNK1MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-B | [1,2,4] Triazolo [1,5-C ] quinazolin-5-amine | 拜耳股份有限公司 | 2024-09-10 | — | — | CN | claimed |
| EP-4013508-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | Bayer Aktiengesellschaft (DE) | 2022-06-22 | — | — | EP | claimed |
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | claimed |
| CN-114466850-B | [1,2,4] Triazolo [1,5-C ] quinazolin-5-amine | 拜耳股份有限公司 | 2024-09-10 | — | — | CN | disclosed |
| EP-4013508-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | Bayer Aktiengesellschaft (DE) | 2022-06-22 | — | — | EP | disclosed |
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | disclosed |