Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAK1 | Q13153 | 6/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.33 |
| ▸ | CYP3A7 | P24462 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.33 |
| ▸ | CYP3A43 | Q9HB55 | 2/20 | 0.33 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.33 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.33 |
| ▸ | PAK4 | O96013 | 3/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | IRAK1 | P51617 | 2/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22979183 | 1.00 | PAK1 (0.33) | PAK1ADORA2AADORA1CYP1A2CYP3A4 | |
| SCHEMBL22980138 | 0.91 | ADORA2A (0.37) | ADORA2AADORA1MKNK1MKNK2ADORA3 | |
| SCHEMBL29645871 | 0.91 | ADORA2A (0.37) | ADORA2AADORA1MKNK1MKNK2ADORA3 | |
| SCHEMBL29646077 | 0.90 | PAK1 (0.34) | PAK1CYP1A2CYP3A4CYP3A5CYP3A7 | |
| SCHEMBL22979075 | 0.90 | PAK1 (0.34) | PAK1CYP1A2CYP3A4CYP3A5CYP3A7 | |
| SCHEMBL22979395 | 0.89 | HDAC1 (0.35) | ADORA2AADORA1CYP1A2CYP3A4CYP3A5 | |
| SCHEMBL22979232 | 0.89 | KDM5A (0.36) | PAK1ADORA2AADORA1CYP1A2CYP3A4 | |
| SCHEMBL22980020 | 0.89 | ADORA2A (0.38) | PAK1ADORA2AADORA1 | |
| SCHEMBL22979892 | 0.88 | ADORA2A (0.33) | ADORA2AADORA1CYP1A2CYP3A4CYP3A5 | |
| SCHEMBL22979811 | 0.88 | ADORA2A (0.34) | ADORA2AADORA1MKNK1MKNK2ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-B | [1,2,4] Triazolo [1,5-C ] quinazolin-5-amine | 拜耳股份有限公司 | 2024-09-10 | — | — | CN | claimed |
| EP-4013508-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | Bayer Aktiengesellschaft (DE) | 2022-06-22 | — | — | EP | claimed |
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | claimed |