SCHEMBL29646271

SCHEMBL29646271

O=C1/C(=C/c2ccc(O)c(O)c2)Oc2ccccc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
STK17B O94768 15/20 1.00
MEN1 O00255 3/20 1.00
RECQL P46063 3/20 1.00
KMT2A Q03164 3/20 1.00
AURKA O14965 3/20 1.00
GSK3B P49841 3/20 1.00
HDAC3 O15379 3/20 1.00
HDAC4 P56524 3/20 1.00
HDAC1 Q13547 3/20 1.00
HDAC7 Q8WUI4 3/20 1.00
HDAC2 Q92769 3/20 1.00
HDAC10 Q969S8 3/20 1.00
HDAC11 Q96DB2 3/20 1.00
HDAC8 Q9BY41 3/20 1.00
HDAC6 Q9UBN7 3/20 1.00
HDAC9 Q9UKV0 3/20 1.00
HDAC5 Q9UQL6 3/20 1.00
TDP1 Q9NUW8 1/20 1.00
PRKAB2 O43741 1/20 1.00
EGFR P00533 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3709614 1.00 STK17B (1.00) STK17BMEN1RECQLKMT2AAURKA
SCHEMBL3709615 1.00 STK17B (1.00) STK17BMEN1RECQLKMT2AAURKA
SCHEMBL21199305 0.87 STK17B (0.76) STK17BMEN1RECQLKMT2AAURKA
SCHEMBL10921543 0.85 STK17B (0.74) STK17BMEN1RECQLKMT2AAURKA
SCHEMBL19462733 0.84 STK17B (0.89) STK17BMEN1RECQLKMT2AAURKA
SCHEMBL19499394 0.84 STK17B (0.89) STK17BMEN1RECQLKMT2AAURKA
Sulfuretin SCHEMBL634006 0.84 MEN1 (1.00) STK17BMEN1RECQLKMT2AAURKA
Sulfuretin SCHEMBL634007 0.84 MEN1 (1.00) STK17BMEN1RECQLKMT2AAURKA
Sulfuretin SCHEMBL30214394 0.84 MEN1 (1.00) STK17BMEN1RECQLKMT2AAURKA
SCHEMBL30337058 0.84 STK17B (1.00) STK17BMEN1RECQLKMT2AAURKA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4615506-A1 USE OF GSK-3 ACTIVATIOR TO MODULATE PROTEASOME ACTIVITY TO PREVENT AGEING ASSOCIATED CONDITIONS AND DISEASES Sahin, Fikret (TR) 2025-09-17 EP claimed
WO-2024258363-A1 USE OF GSK-3 ACTIVATIOR TO MODULATE PROTEASOME ACTIVITY TO PREVENT AGEING ASSOCIATED CONDITIONS AND DISEASES SAHIN FIKRET (TR) 2024-12-19 WO claimed
US-20230107927-A1 METHODS OF TREATING IATROGENIC AUTOIMMUNE COLITIS FIRST WAVE BIO, INC. 2023-04-06 US claimed
EP-4615869-A1 COMBINATION THERAPY COMPRISING BISPECIFIC ANTIBODIES COMPRISING AN NRP1 BINDING DOMAIN Pinetree Therapeutics, Inc. (US) 2025-09-17 EP disclosed
EP-4615506-A1 USE OF GSK-3 ACTIVATIOR TO MODULATE PROTEASOME ACTIVITY TO PREVENT AGEING ASSOCIATED CONDITIONS AND DISEASES Sahin, Fikret (TR) 2025-09-17 EP disclosed
WO-2024258363-A1 USE OF GSK-3 ACTIVATIOR TO MODULATE PROTEASOME ACTIVITY TO PREVENT AGEING ASSOCIATED CONDITIONS AND DISEASES SAHIN FIKRET (TR) 2024-12-19 WO disclosed
WO-2024178274-A2 METHODS OF DEGRADING RAF(RAF) PROTEIN IN CELLS USING MITOGEN-ACTIVATED PROTEIN KINASE KINASE 1/2 (MEK1/2) PROTEIN DEGRADERS INSTITUTE FOR CANCER RESEARCH D/B/A THE RESEARCH INSTITUTE OF FOX CHASE CANCER CENTER (US) 2024-08-29 WO disclosed
WO-2024102187-A1 COMBINATION THERAPY COMPRISING BISPECIFIC ANTIBODIES COMPRISING AN NRP1 BINDING DOMAIN PINETREE THERAPEUTICS, INC. (US) 2024-05-16 WO disclosed
EP-3723801-B9 TREATMENT OF A DISEASE OF THE GASTROINTESTINAL TRACT WITH A S1P MODULATOR BIORA THERAPEUTICS INC (US) 2023-10-04 EP disclosed
EP-3723801-B1 TREATMENT OF A DISEASE OF THE GASTROINTESTINAL TRACT WITH A S1P MODULATOR BIORA THERAPEUTICS INC (US) 2023-06-07 EP disclosed
US-20230107927-A1 METHODS OF TREATING IATROGENIC AUTOIMMUNE COLITIS FIRST WAVE BIO, INC. 2023-04-06 US disclosed
CN-115282165-A Natural killer cells from placenta 细胞结构公司 2022-11-04 CN disclosed
CN-115137753-A Natural killer cells from placenta 细胞结构公司 2022-10-04 CN disclosed
US-20220135666-A1 TREATMENT OF A DISEASE OF THE GASTROINTESTINAL TRACT WITH A S1P MODULATOR GLAS USA LLC 2022-05-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220135666-A1 TREATMENT OF A DISEASE OF THE GASTROINTESTINAL TRACT WITH A S1P MODULATOR S1PR2, S1PR1, S1PR4 STK17B 2341/4885MEN1 306/4885RECQL 2116/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.