SCHEMBL29646501 — predicted protein targets

Predicted protein targets (top 12)

	gene	UniProt	supporting neighbours	confidence
▸	KDM4E	B2RXH2	1/20	0.46

▸	ALDH1A1	P00352	1/20	0.46

▸	POLB	P06746	1/20	0.46

▸	MAPT	P10636	6/20	0.44

▸	THRB	P10828	3/20	0.44

▸	ADORA3	P0DMS8	8/20	0.41

▸	TP53	P04637	2/20	0.40

▸	ADORA2A	P29274	2/20	0.39

▸	ADORA1	P30542	2/20	0.39

▸	XDH	P47989	1/20	0.38

▸	RXFP1	Q9HBX9	1/20	0.37

▸	SMN1; SMN2	Q16637	2/20	0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29645586	0.93	KDM4E (0.48)	KDM4EALDH1A1POLBMAPTTHRB
SCHEMBL29645416	0.92	KDM4E (0.45)	KDM4EALDH1A1POLBMAPTTHRB
SCHEMBL29645882	0.91	KDM4E (0.44)	KDM4EALDH1A1POLBMAPTTHRB
SCHEMBL29645929	0.90	KDM4E (0.47)	KDM4EALDH1A1POLBMAPTTHRB
SCHEMBL29645574	0.89	KDM4E (0.48)	KDM4EALDH1A1POLBMAPTTHRB
SCHEMBL29645741	0.89	KDM4E (0.48)	KDM4EALDH1A1POLBMAPTTHRB
SCHEMBL29645699	0.88	KDM4E (0.47)	KDM4EALDH1A1POLBMAPTTHRB
SCHEMBL29645839	0.88	KDM4E (0.47)	KDM4EALDH1A1POLBMAPTTHRB
SCHEMBL29646008	0.88	KDM4E (0.47)	KDM4EALDH1A1POLBMAPTTHRB
SCHEMBL29646140	0.87	POLB (0.45)	KDM4EALDH1A1POLBMAPTTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-114466850-A	[1,2,4] triazolo [1,5-C ] quinazolin-5-amines	拜耳股份有限公司	2022-05-10	—	—	CN	disclosed