SCHEMBL296467

SCHEMBL296467

CC1CC(C)(C)CC(c2ccc(O)c(C(C)C)c2)(c2ccc(O)c(C(C)C)c2)C1

nearest known ligand 0.60

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 3/20 0.60
ESR2 Q92731 3/20 0.60
GABRA1 P14867 1/20 0.32
GABRB2 P47870 1/20 0.32
CCR2 P41597 6/20 0.32
HSP90AA1 P07900 3/20 0.32
HSP90AB1 P08238 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29459396 1.00 ESR1 (0.60) ESR1ESR2GABRA1GABRB2CCR2
SCHEMBL6258466 0.91 ESR1 (0.50) ESR1ESR2HSP90AA1HSP90AB1
SCHEMBL7066671 0.88 ESR1 (0.56) ESR1ESR2
SCHEMBL299794 0.84 ESR1 (0.56) ESR1ESR2GABRA1GABRB2
SCHEMBL21538491 0.84 ESR1 (0.69) ESR1ESR2
SCHEMBL29404012 0.81 ESR1 (0.65) ESR1ESR2CCR2
SCHEMBL29459501 0.81 ESR1 (0.65) ESR1ESR2CCR2
SCHEMBL244496 0.81 ESR1 (0.65) ESR1ESR2CCR2
SCHEMBL7914460 0.80 ESR1 (0.56) ESR1ESR2GABRA1GABRB2
SCHEMBL7909628 0.80 ESR1 (0.63) ESR1ESR2CCR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 340 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1763560-A1 POLYARYLATE COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 2007-03-21 EP claimed
US-7109274-B2 Polyarylate compositions GENERAL ELECTRIC COMPANY (US) 2006-09-19 US claimed
WO-2006012161-A1 POLYARYLATE COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 2006-02-02 WO claimed
US-20060004152-A1 Polyarylate compositions GENERAL ELECTRIC COMPANY 2006-01-05 US claimed
EP-1560871-A1 METHOD FOR MAKING COPOLYCARBONATES GENERAL ELECTRIC COMPANY (US) 2005-08-10 EP claimed
WO-2004041907-A1 METHOD FOR MAKING COPOLYCARBONATES GENERAL ELECTRIC COMPANY (US) 2004-05-21 WO claimed
US-6657038-B1 Melt condensation copolymerization of dihydroxyaromatic compounds and diphenyl carbonate derivative in presence of metal hydroxide and quaternary phosphonium salt GENERAL ELECTRIC COMPANY 2003-12-02 US claimed
US-6576739-B2 Conversion of the hindered bisphenol to the corresponding bischloroformate and subsequent treatment with an amine catalyst and an aqueous base to effect polymerization by hydrolysis and condenstation of bischloroformate groups GENERAL ELECTRIC COMPANY 2003-06-10 US claimed
US-20020111456-A1 Method of polycarbonate preparation SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2002-08-15 US claimed
WO-2001085825-A2 METHOD OF POLYCARBONATE PREPARATION GENERAL ELECTRIC COMPANY (US) 2001-11-15 WO claimed
US-11936103-B2 Conductive film for antennas, and antenna TEIJIN LIMITED (JP) 2024-03-19 US disclosed
US-11898025-B2 Polyethylene with additives for increased environmental stress crack resistance SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2024-02-13 US disclosed
US-20230006341-A1 CONDUCTIVE FILM FOR ANTENNAS, AND ANTENNA TEIJIN LIMITED (JP) 2023-01-05 US disclosed
US-11535732-B2 Polyethylene with polycarbonate-siloxane for increased environmental stress crack resistance SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2022-12-27 US disclosed
EP-4052904-A1 CONDUCTIVE FILM FOR ANTENNAS, AND ANTENNA Teijin Limited (JP) 2022-09-07 EP disclosed
US-20020035234-A1 Continuous preparation of polycarbonate GENERAL ELECTRIC COMPANY 2002-03-21 US disclosed
WO-2002008311-A2 CONTINUOUS PREPARATION OF POLYCARBONATE GENERAL ELECTRIC COMPANY (US) 2002-01-31 WO disclosed
WO-2001085825-A2 METHOD OF POLYCARBONATE PREPARATION GENERAL ELECTRIC COMPANY (US) 2001-11-15 WO disclosed
US-6284931-B1 REACTION OF 3,3,5-TRIMETHYLCYCLOHEXANONE AND PHENOL TO FORM DIPHENOL DERIVATIVE HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2001-09-04 US disclosed
EP-0995737-A1 Process for producing 3,3,5-trimethylcyclohexylidenebisphenols Honshu Chemical Industry Co. Ltd. (JP) 2000-04-26 EP disclosed