SCHEMBL296468

SCHEMBL296468

O=[C]NC(F)(F)CF

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20899875 0.69
SCHEMBL392107 0.67
SCHEMBL14815650 0.63
SCHEMBL8027620 0.63
SCHEMBL1767286 0.63
SCHEMBL8009414 0.63
SCHEMBL1766666 0.63
SCHEMBL7564866 0.60
SCHEMBL1144410 0.60
SCHEMBL1767136 0.59

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 202 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3864015-B1 PROCESS FOR THE PREPARATION OF IMIDAZOLE DERIVATEIVES BAYER AG (DE) 2023-05-10 EP claimed
CN-110312718-B Heterocyclene derivatives as pest control agents 拜耳公司 2023-02-28 CN claimed
EP-3864016-B1 PROCESS FOR PREPARING SUBSTITUTED IMIDAZOLE DERIVATIVES BAYER AG (DE) 2022-09-14 EP claimed
US-20220009930-A1 PROCESS FOR PREPARING IMIDAZOLE DERIVATIVES BAYER AKTIENGESELLSCHAFT (DE) 2022-01-13 US claimed
US-20210380611-A1 PROCESS FOR PREPARING SUBSTITUTED IMIDAZOLE DERIVATIVES BAYER AKTIENGESELLSCHAFT (DE) 2021-12-09 US claimed
EP-3864015-A1 PROCESS FOR PREPARING IMIDAZOLE DERIVATIVES Bayer Aktiengesellschaft (DE) 2021-08-18 EP claimed
EP-3864016-A1 PROCESS FOR PREPARING SUBSTITUTED IMIDAZOLE DERIVATIVES Bayer Aktiengesellschaft (DE) 2021-08-18 EP claimed
US-11083199-B2 Heterocycle derivatives as pesticides BAYER AKTIENGESELLSCHAFT (DE) 2021-08-10 US claimed
CN-112867713-A Process for preparing imidazole derivatives 拜耳公司 2021-05-28 CN claimed
CN-112805286-A Process for preparing substituted imidazole derivatives 拜耳公司 2021-05-14 CN claimed
US-20200045976-A1 HETEROCYCLE DERIVATIVES AS PESTICIDES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2020-02-13 US claimed
EP-3568395-A1 HETEROCYCLENE DERIVATIVES AS PEST CONTROL AGENTS Bayer Aktiengesellschaft (DE) 2019-11-20 EP claimed
WO-2018130443-A1 HETEROCYCLENE DERIVATIVES AS PEST CONTROL AGENTS BAYER AKTIENGESELLSCHAFT (DE) 2018-07-19 WO claimed
US-9938281-B2 Purine inhibitors of human phosphatidylinositol 3-kinase delta MERCK SHARP & DOHME CORP. (US) 2018-04-10 US claimed
US-7879852-B2 such as (4S)-1-{[(3S,4R)-1-tert-butyl-4-(2,4-difluorophenyl)pyrrolidine-3-yl]carbonyl}-4-[(4,4-dimethylcyclohexyl)(2,2-dimethylpropanoyl)amino]-N,N-dimethyl-L-prolineamide, used for the treatment of obesity, diabetes, inflammation and erectile dysfunction LG LIFE SCIENCES LTD. (KR) 2011-02-01 US claimed
US-20090298829-A1 MELANOCORTIN RECEPTOR AGONISTS LG LIFE SCIENCES LTD. (KR) 2009-12-03 US claimed
EP-3957627-B1 6-MEMBERED HETEROCYCLIC DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME SHIONOGI & CO (JP) 2024-06-19 EP disclosed
WO-2024108198-A2 METHODS OF TREATING OBESITY WITH AN MC4R AGONIST RHYTHM PHARMACEUTICALS, INC. (US) 2024-05-23 WO disclosed
WO-2002062764-A1 FUSED HETEROCYCLIC COMPOUNDS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2002-08-15 WO disclosed
EP-0316097-A1 Naphtho(2,1-b)furan derivatives IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1989-05-17 EP disclosed